DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5026 and Sbf1

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_038934802.1	Gene:	Sbf1 / 300147	RGDID:	1307090	Length:	1950	Species:	Rattus norvegicus

Alignment Length:	536	Identity:	138/536 - (25%)
Similarity:	210/536 - (39%)	Gaps:	158/536 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 STLTVGAGI-PHPLQNGYAIEALAC--GVGGVGGGALQS--PQASCE-WRITNVNRDFSVCATYG 230
            ||||..:.: |.......::...||  ....:|.|.|.|  .:|..| :||:.|||.:::|.:|.
  Rat  1159 STLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYP 1223

  Fly   231 ATLIVPKAITDEQIV-LSAAFRDGGRFPVLSYRH-ENGATLMRSS-----------------QPL 276
            ..||||::|.|..:. :|..:|. .||||:.:|. .:.|.|:||.                 .|.
  Rat  1224 GLLIVPQSIQDNALQRVSRCYRQ-NRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNTPSPG 1287

  Fly   277 SIQGIKRCRADEAILNLVLGRSRKGFIVDTWGKGKSNTETDLHY--------------------- 320
            ..|........|..|..|:....:  ..|:.|:...::.:..|.
  Rat  1288 QAQADSSSLEQEKYLQAVVSSMPR--YADSSGRNTLSSFSSAHMGGHVPSPRARVTTLSNPLAAS 1350

  Fly   321 --------SQWKKVNRS---------IGN-------VSSP------------------------- 336
                    .:|..|..|         :|:       :|:|
  Rat  1351 ASRWTASRGKWSSVRASGRSSGLGADVGSRLAGRDLLSTPHTNGAPPDSGFLRPQRAALYIIGDK 1415

  Fly   337 ------------------------ASILDSFARLIEACNDLGC-----STDKWLSRLENSGWLSL 372
                                    ..:..||.:|::||.. ||     |...:|..||:|.||..
  Rat  1416 AQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVP-GCPATEPSPASFLRSLEDSEWLIQ 1479

  Fly   373 VLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQA 437
            :...|..|.:|.:.|| .||.|||....|.|.|..|.||||::.:|..||:.|.:.|:|:||:..
  Rat  1480 IHKLLQISVLVVELLD-SGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSF 1543

  Fly   438 GHPFASRHRYSCYTPNQTRNKTSGAT--FVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQ 500
            ||.|:.|..::      ...::||.|  |:.||||::|::.|||..||||...|..|..|....:
  Rat  1544 GHRFSHRGAHT------LAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHTSRR 1602

  Fly   501 YGTFLCDSERERNELNV----------HTRTTSLWSYLNR-----PDVLQTFLNPLYEP-NANVI 549
            :.|||.||:.||.||.:          .....|:|.|::|     |    .|.|..|.| :..|:
  Rat  1603 FRTFLLDSDYERIELGLLYEEKGERRGQLACKSVWEYVDRLSKRTP----MFYNYTYAPEDTEVL 1663

  Fly   550 WPSVAPISLELWSDLY 565
            .|.....:|::| |.|
  Rat  1664 RPYSNVSNLKVW-DFY 1678

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	119/464 (26%)
Sbf1	XP_038934802.1	uDENN	<97..132	CDD:397495
		DENN	178..367	CDD:214823
		dDENN	421..489	CDD:129037
		SBF2	600..821	CDD:403522
		PH-like	950..1068	CDD:418428
		PTP_DSP_cys	1207..1579	CDD:421693	91/382 (24%)
		PH_Sbf1_hMTMR5	1843..1948	CDD:269941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349517
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840