Protein Alignment CG5026 and Mtmr4

DIOPT Version :10

• Sequence 1: NP_648271.3
• Gene: CG5026 / 39026
• FlyBaseID: FBgn0035945
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_001099297.4
• Gene: Mtmr4 / 287607
• RGDID: 1310306
• Length: 1191
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 149/593 - (25%)
• Similarity: 237/593 - (39%)
• Gaps: 182/593 - (30%)

  Fly    59 IDCVEKKPSLSQNIVVGGIITLKCKDLRIISLEIKCGKEFFNVAASLEALSAIQNT-------EL 116
            ||.||.:.....:|.        |||.::    ::|  .|.......|.||.:...       |.
  Rat    76 IDSVESRDMFQLHIA--------CKDSKV----VRC--HFSTFKQCQEWLSRLSRATARPAKPED 126

  Fly   117 LYPFFYRPMYSIL--EDGYTMF---------RPELEFAKLISGVGMGGASSPNVANITICMPSTS 170
            |:.|.|......|  ||.:|..         |.|.|.|::       |....||
  Rat   127 LFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARM-------GFDLQNV----------- 173

  Fly   171 TSTLTVGAGIPHPLQNGYAIEALACGVGGVGGGALQSPQASCEWRITNVNRDFSVCATYGATLIV 235
                                                       ||::::|.::.:|.:|...|:|
  Rat   174 -------------------------------------------WRVSHINSNYKLCPSYPQKLLV 195

  Fly   236 PKAITDEQIVLSAAFRDGGRFPVLSYRH-ENGATLMRSSQP------------------------ 275
            |..|||:::...|:||...|.||:.||| .|||.:.|.|||
  Rat   196 PVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACA 260

  Fly   276 -------------------------------LSIQGIKRCRADEAILNL--------VLGRSRKG 301
                                           .:..|::...|.:.:|.|        |..|::.|
  Rat   261 LDPGTRASGGSLSAGTNDASEACDTDFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGG 325

  Fly   302 FIVDTWGKGKSNTETDLHYSQWKKVNRSIGNVSSPASILDSFARLIEACNDLGCSTDKWLSRLEN 366
                       ..|.:.:|...:.|...:.|:.   :|.:||..|...|:.:. ....|||.||:
  Rat   326 -----------GCECEEYYPNCEVVFMGMANIH---AIRNSFQYLRAVCSQMP-DPSNWLSALES 375

  Fly   367 SGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIE 431
            :.||..:...|.|:.:||..:|:||.|||||.:.|.|.|..:.:|.:|:|:|..||:.|.|.|:|
  Rat   376 TKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVE 440

  Fly   432 REWIQAGHPFASR--HRYSCYTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFE 494
            .:|:..||.|..|  |:.:....|:     ....|:.:||.::||..||||.|||:...|:.|.:
  Rat   441 SDWLDFGHKFGDRCGHQENAEDQNE-----QCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQ 500

  Fly   495 HSHFSQYGTFLCDSERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLYEPNANVIWPSVAPI-SL 558
            |::...|||||.::..||.:.|::.||.|:|:.|...:  :.|.|.||.|.::::...|..: :|
  Rat   501 HTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGN--KNFHNFLYTPGSDMVLHPVCHVRAL 563

  Fly   559 ELWSDLYL 566
            .||:.:||
  Rat   564 HLWTAVYL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_648271.3	PH-GRAM_MTMR9	1..106	CDD:275398	10/46 (22%)
		Myotub-related	210..512	CDD:461958	102/367 (28%)
Mtmr4	NP_001099297.4	PH-GRAM_MTMR4	23..136	CDD:270150	17/73 (23%)
		PTP-MTMR4	172..479	CDD:350435	87/380 (23%)
		FYVE_MTMR4	1107..1166	CDD:277272