DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5026 and SPAC19A8.03

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_593789.1	Gene:	SPAC19A8.03 / 2542522	PomBaseID:	SPAC19A8.03	Length:	559	Species:	Schizosaccharomyces pombe

Alignment Length:	615	Identity:	175/615 - (28%)
Similarity:	263/615 - (42%)	Gaps:	139/615 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IKTPKLDGVLLHDPSNAGASGATVGTLCITGHHLLLSARQETSQELWLLHKNID----CVEKKPS 67
            ||..|:..|...:..|     ...|||.:|.:|.:.|. .|..:|:|..:..|:    |..:|
pombe     4 IKVAKVGNVKFVNKGN-----ELNGTLHLTAYHSIFSI-SENGKEIWTAYSMINNVKLCSNEK-- 60

  Fly    68 LSQNIVVGGIITLKCKDLRIISLEIKCGKEFFNVAASLEALSAIQNTELLYPFFYRPMYSILEDG 132
                   ...|.::|:|........:..::..:|..:|:.|.:|.:..:||.|:|.|
pombe    61 -------SFCIRIQCRDFMFFCWRFQSTEDAMDVYDTLQELMSINSINMLYAFYYMP-------- 110

  Fly   133 YTMFRPELEFAKLISGVGMGGASSPNVANITICMPSTSTSTLTVGAGIPHPLQNGYAIEALACGV 197
                               .|....        :||:..|.|         |:|.|.    ..||
pombe   111 -------------------SGDEEK--------LPSSWKSFL---------LENEYR----RMGV 135

  Fly   198 GGVGGGALQSPQASCEWRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSYR 262
                |.:.|:..|...||||.:|.::|.|.:|...|.||.:|:|..|.....:|...|||.|:|.
pombe   136 ----GDSTQADGAGGNWRITKINENYSECHSYPQALAVPASISDSVIYYGCKYRSKNRFPTLTYL 196

  Fly   263 HENGATLMRSSQPLSIQGIKRCRA--DEAILNLVLGRS----RKGFIVD-----------TWGKG 310
            |:|..::.|:||||  .||::.|:  ||.::..:...|    ::..|||           ..|.|
pombe   197 HKNSFSITRASQPL--VGIRQNRSAQDEKLVEAIFATSIIPGKENLIVDARPSTNAMANIAVGAG 259

  Fly   311 KSNTETDLHYSQWKKVNRSIGNVSSPASILDSFARLIEACNDLGCSTDKWLSRLEN-SGWLSLVL 374
            ..|.:   ||...||:...|.|:.   .:.||..:::.|..:...|....|..|.| |.||..:.
pombe   260 SENMD---HYRFAKKIYLGIDNIH---VMRDSLNKIVNALKNTDISAAPPLIELLNRSSWLKHLA 318

  Fly   375 NSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGH 439
            |.|..:.::.:.:....:.||||.:.|.|.|..:.:|.|:.|:|..||:.|..||:|::|:..||
pombe   319 NILQGAVLIVKTVHFRHAHVLVHCSDGWDRTSQLCALPQLCLDPYYRTIEGFFALVEKDWLSFGH 383

  Fly   440 PFASR-------------HRYS------------CYTPNQTRNKTSG-----------ATFVLFL 468
            .||.|             ..||            .||.:..|:..||           ..|..||
pombe   384 RFAERCCHLPGKRIFTIDSSYSEEPPQSSPSSTLQYTFSTVRSALSGFSIDHSEKMMSPVFHQFL 448

  Fly   469 DCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSLWSY-LNRPD 532
            ||::|:..|||..|||:.:.|..|..|.:..|||:||.:|||||.:.:|.|.|..:|.| |:|.|
pombe   449 DCVWQIMDQFPNCFEFNERFLRRLLYHLYSCQYGSFLYNSERERAQASVSTHTRCIWDYFLSRKD 513

  Fly   533 VLQTFLNPLYEPNANVIWPSVAPISLELWS 562
               .|.||.|.|..:||.|.  |.||..||
pombe   514 ---EFKNPNYVPYDDVIMPD--PSSLRWWS 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398	21/102 (21%)
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	127/447 (28%)
SPAC19A8.03	NP_593789.1	PH-like	4..94	CDD:302622	22/104 (21%)
SPAC19A8.03	NP_593789.1	Myotub-related	103..491	CDD:284109	127/447 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1089
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10807
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910