Protein Alignment CG5026 and mtm-1

DIOPT Version :10

• Sequence 1: NP_648271.3
• Gene: CG5026 / 39026
• FlyBaseID: FBgn0035945
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_491531.2
• Gene: mtm-1 / 172148
• WormBaseID: WBGene00003475
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 644
• Identity: 158/644 - (24%)
• Similarity: 258/644 - (40%)
• Gaps: 163/644 - (25%)

  Fly    24 GASGATVGTLCITGHHLL-LSARQETSQELWLLH---KNIDCVEKKPSLSQNIVVGGI----ITL 80
            |..|...|.:.||.:.:: |........|.|.|.   ..:..:||....:.::...|.    .|:
 Worm    45 GPLGKFPGKIVITRYRMVFLVGDGGKMYEQWKLDIPLGQVSRIEKVGRKTTSVAKRGDDNYGFTI 109

  Fly    81 KCKDLRIISLEIK-CGKEFFNVAASLEALSAIQNTELLYPFFYR-PMYS---------ILEDGYT 134
            .|||.|:...... ...:..||..||...:        :|..:. ||::         :::||:.
 Worm   110 YCKDYRVYRFTCNPASSDRKNVCDSLNRYA--------FPLSHNLPMFASVHAAETPRLMKDGWK 166

  Fly   135 MFRPELEFAKLISGVGMGGASSPNVANITICMPSTSTSTLTVGAGIPHPLQNGYAIEALACGVGG 199
            ::..|.|:.:|                                 |||:
 Worm   167 IYSAEKEYERL---------------------------------GIPN----------------- 181

  Fly   200 VGGGALQSPQASCEWRITNVNRDFSVCATYGATLIVPKAITDEQ---IVLSAAFRDGGRFPVLSY 261
                       |..|:..::|:|:....||..|.::|....:|.   :.....||...|.||||:
 Worm   182 -----------SRLWKEVDINKDYKFSETYPRTFVIPTVSWEEGKPFVKKLGEFRSKERIPVLSW 235

  Fly   262 RHENG-ATLMRSSQPLS-IQGIKRCRADEAILNLVLGRS---RKGFIVDTWGKGKSNTETDLHYS 321
            .::.. |::.|.|||:: |.| ||...||..|..::..:   |:..|:|  .:...|.
 Worm   236 INQTTLASISRCSQPMTGISG-KRSAEDERHLTNIMNANANCRELLILD--ARPAVNA------- 290

  Fly   322 QWKKVNRSIGN------VSSPASIL---------DSFARLIEA----CNDLGCSTDKWLSRLENS 367
               |:|::.|.      |::|.:.|         ||..||:.|    .::.|     :...|:.|
 Worm   291 ---KLNKAKGGGYEENYVNAPLTFLNIHNIHVVRDSLKRLLAALIPRVDEKG-----YYKALDES 347

  Fly   368 GWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIER 432
            .||:.|.:.|..:......:|.|...||:|.:.|.|.|..:|||..|.|:...||:.|...|||:
 Worm   348 KWLNHVQSILEGAVKAVFNVDTEKQSVLIHCSDGWDRTAQLTSLAMIQLDSYYRTIEGFIVLIEK 412

  Fly   433 EWIQAGHPFASR--HRYSCYTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEH 495
            ||...||.|..|  |....|:..:     ....||.|.||::|:..|||.:|||:.:|||.:.:.
 Worm   413 EWCSFGHKFGERIGHGDDNYSDGE-----RSPVFVQFCDCLWQIMRQFPWAFEFTQELLICMLDE 472

  Fly   496 SHFSQYGTFLCDSERER-NELNVHTRTTSLWSYL--NRPDVLQTFLNPLYEP-------NANVIW 550
            .:..:|||||.:||:.| .:......|.|.|||:  |:    :.|.||:::.       |.|
 Worm   473 LYACRYGTFLYNSEKIRLKDKKCDETTISFWSYVLENK----KKFRNPMFKHGKSNKVINVN--- 530

  Fly   551 PSVAPISLELWSDLYLR---WVIDQRSSVTVMSQIQELVTREKELRTQALKLRKQAMEL 606
            ||:.  .|.:|.|.|.|   :|:..... .|.....:.|..:|:|..:.:.|...|.:|
 Worm   531 PSLC--GLHVWIDYYARSNPYVVTPNHE-DVQQPGAQFVDEKKQLLDEIMALDDAAQKL 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_648271.3	PH-GRAM_MTMR9	1..106	CDD:275398	20/90 (22%)
		Myotub-related	210..512	CDD:461958	99/330 (30%)
mtm-1	NP_491531.2	PH-GRAM_MTM-like	36..141	CDD:275407	21/103 (20%)
		Myotub-related	163..489	CDD:461958	107/409 (26%)