DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5026 and mtmr3

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_031747519.1	Gene:	mtmr3 / 100494490	XenbaseID:	XB-GENE-984945	Length:	1224	Species:	Xenopus tropicalis

Alignment Length:	414	Identity:	130/414 - (31%)
Similarity:	194/414 - (46%)	Gaps:	72/414 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 WRITNVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSYRHE-NGATLMRSSQP-L 276
            |||:|:|..|.:|.:|...||:|..|||:::...|:||...|.|.:.|||: |||.:.|..|| :
Frog   176 WRISNINEKFRLCPSYPQELIIPAWITDKELESVASFRSWKRIPAVVYRHQSNGAVIARCGQPEV 240

  Fly   277 S------------IQGI-KRCRADEA--------------------ILN---------------- 292
            |            :|.: |.|..|.:                    :|.
Frog   241 SWWGWRNADDEHLVQSVAKACATDSSRASPGKMTNGSCPRNQINGGVLTDVDFESSMSNIPPPES 305

  Fly   293 --------LVLGRSRKGFIVDTWGKGKSNTETDLHYSQWKKVNRSIGNVSSPASILDSFARLIEA 349
                    |:|........|....|| ...|...:|...:.|...:.|:.   ||..||..|...
Frog   306 PSVQPQKLLILDARSYAAAVANRAKG-GGCECPEYYPNCEVVFMGMANIH---SIRKSFQSLRLL 366

  Fly   350 CNDLGCSTDKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQI 414
            |..:. ....|||.||.:.||..:...|.:|.:|...||::..|||||.:.|.|.|..:.:|.::
Frog   367 CTQMP-DPANWLSALEGTKWLQHLSMLLKSSLLVVHTLDKDQRPVLVHCSDGWDRTPQIVALSKL 430

  Fly   415 ILNPDCRTVRGLQALIEREWIQAGHPFASRHRYSC-YTPNQTRNKTSGATFVLFLDCIYQLYTQF 478
            :|:|..||:.|.|.|:|.||:..||.||.|    | :..|..........|:.:|||::||..||
Frog   431 LLDPYYRTIEGFQVLVETEWLDFGHKFADR----CGHGENSEDLNERCPVFLQWLDCVHQLQRQF 491

  Fly   479 PCSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLYE 543
            ||||||:...|:.|.:|::...:|||||::.:||:|.::..||.|:||.|...:  :.|.|.||.
Frog   492 PCSFEFNEGFLVKLVQHTYSCLFGTFLCNNAKERSEKHIQERTCSVWSLLRAGN--RAFKNLLYS 554

  Fly   544 PNA-NVIWPSVAPISLELWSDLYL 566
            ..: .|::|.....:|.|||.:||
Frog   555 SQSETVLYPVCHVRNLMLWSAVYL 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	109/356 (31%)
mtmr3	XP_031747519.1	PH-like	23..115	CDD:418428
		PTP-MTMR3	169..486	CDD:350434	91/318 (29%)
		FYVE_MTMR3	1137..1206	CDD:277271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010