DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5026 and LOC100333801

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_005171779.4	Gene:	LOC100333801 / 100333801	-ID:	-	Length:	955	Species:	Danio rerio

Alignment Length:	472	Identity:	141/472 - (29%)
Similarity:	217/472 - (45%)	Gaps:	91/472 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 LTVGAGIPHPLQNGYAIEALAC-------------GVGGVGGGALQSPQ--------ASCEWRIT 217
            ::..:|.|..||..:|...|:|             |:...||...:..:        ....|||:
Zfish   104 ISAASGPPARLQELFAFSFLSCSNSVTAEDREVHDGICRAGGHKQRFKRELQRMGFDTHSAWRIS 168

  Fly   218 NVNRDFSVCATYGATLIVPKAITDEQIVLSAAFRDGGRFPVLSYRHE-NGATLMRSSQP-LS--- 277
            |:|.::.||::|...::||.|:||:|:...||||...|.|.:.|||: :||.:.|..|| :|
Zfish   169 NINSNYRVCSSYPEQILVPAAVTDQQLENVAAFRSWKRIPAVVYRHQSSGAVIGRCGQPEVSWWG 233

  Fly   278 ---------IQGIKRCRADEAILNLVLGR--------------------------------SRKG 301
                     :|.|.:..|.:...|..|..                                |:|.
Zfish   234 WRNADDEHLVQAIAKACATDPAANTALANGSCVHNHANGTISGSDPHMANGKVEAEPSATPSQKL 298

  Fly   302 FIVD---------TWGKGKSNTETDLHYSQWKKVNRSIGNVSSPASILDSFARLIEACNDLGCST 357
            .|:|         ...|| ...|...:|...:.:...:.|:.   ||..||..|...|..:....
Zfish   299 LIMDARSYAAAVANRAKG-GGCECPEYYPNCEVMFMGMANIH---SIRKSFQCLRTLCAQVPDPL 359

  Fly   358 DKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRT 422
            : |||.||.:.||..:...|.||.:|...:|::..|||||.:.|.|.|..:.:|.:::|:|..||
Zfish   360 N-WLSALEGTKWLQHLSLLLKASVLVVNAVDRDHRPVLVHCSDGWDRTPQILALSKLMLDPFYRT 423

  Fly   423 VRGLQALIEREWIQAGHPFASR--HRYSCYTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFS 485
            :.|.:.|:|.||:..||.|:.|  |.......|:     ....|:.:|||::||..||||||:|:
Zfish   424 IEGFEVLVETEWLDFGHKFSERCGHGERADDVNE-----RCPVFLQWLDCVHQLQRQFPCSFQFN 483

  Fly   486 TQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLYEPNANVIW 550
            ...|:.|.:|::...:|||||:|.:||.|..|..:|.|:||.| || ..|:|.|.||.|.:..:.
Zfish   484 EAFLVKLVQHTYSCLFGTFLCNSVKEREEQRVQEKTCSVWSLL-RP-ANQSFHNILYSPRSETVL 546

  Fly   551 PSVAPI-SLELWSDLYL 566
            ..|..: :|.|||.:||
Zfish   547 RPVCHVRNLMLWSAVYL 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	117/414 (28%)
LOC100333801	XP_005171779.4	PH-like	21..122	CDD:327399	5/17 (29%)
		Myotub-related	149..511	CDD:310891	108/371 (29%)
		FYVE_like_SF	871..926	CDD:333710
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010