DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5026 and sbf1

DIOPT Version :9

Sequence 1:	NP_001163392.1	Gene:	CG5026 / 39026	FlyBaseID:	FBgn0035945	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_012813917.1	Gene:	sbf1 / 100125154	XenbaseID:	XB-GENE-1013544	Length:	1923	Species:	Xenopus tropicalis

Alignment Length:	682	Identity:	157/682 - (23%)
Similarity:	246/682 - (36%)	Gaps:	245/682 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 STSTLTVGAGIPHPLQNGYAIEALAC------GVGGVGGGALQSPQASCEWRITNVNRDFSVCAT 228
            :||||..    |.....|...|...|      |:|.:.....:|...  .:||:.|||.::||.:
Frog  1120 TTSTLKA----PEKQTIGNVAERACCRDYQRMGLGTLSNSLQRSKNE--PFRISTVNRMYAVCNS 1178

  Fly   229 YGATLIVPKAITDEQI-VLSAAFRDGGRFPVLSYRH-ENGATLMRS------------------- 272
            |...||||.:|.|..: .:|..:|. .||||:.:|. .:.|.|:||
Frog  1179 YPGLLIVPHSIQDNTLQKISRCYRQ-NRFPVVCWRSPRSKAVLLRSGGLHGKGVVGLFKSPNTTA 1242

  Fly   273 -----------SQPLSIQGIKRC--RADE---------------------------AILNLVLGR 297
                       .|...:|.:..|  |..|                           :::..|:|.
Frog  1243 VGQSQTDSTSLEQEKYLQAVVNCMPRFAEMSGRNTLSAFPSAHLYDSPDKRQPKLGSLMKQVIGG 1307

  Fly   298 S-----------------RKGFIVD-TWGKGK-----------SNTETDLHYSQWKKVNRS---- 329
            .                 |:|:|.. .||..:           |:..|.|...:....|::
Frog  1308 KEDNRGGYSVRGIKHPAVRRGYIEQGKWGSMRGSGRLSAYAMNSDVGTRLAGRELVTHNQNGGPS 1372

  Fly   330 -------------IGNVSS---------------PASILD------SFARLIEACNDLGCSTD-- 358
                         ||:.|.               |..:.|      ||.:|::||.....|:|
Frog  1373 ESALTPRRAALYIIGDKSQLKGVKQDPLQQWELVPIELFDVRQVKGSFKKLMKACVPSAPSSDPS 1437

  Fly   359 -KWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRT 422
             .:|..||:|.||..:...|..|.:|.:.|| .||.|||....|.|.|..|.||||::.:|..||
Frog  1438 QSYLRTLEDSEWLVQLHKLLQVSVLVVELLD-SGSSVLVGLEDGWDLTTQVVSLVQLLSDPYYRT 1501

  Fly   423 VRGLQALIEREWIQAGHPFASRHRYSCYTPNQTRNKTSGAT--FVLFLDCIYQLYTQFPCSFEFS 485
            :.|.:.|:|:||:..||.|:.|..::      ..::::|.|  |:.||||::|::.|||..||||
Frog  1502 IEGFRLLVEKEWLSFGHRFSHRGAHT------AASQSNGFTPVFLQFLDCVHQVHLQFPSEFEFS 1560

  Fly   486 TQLLILLFEHSHFSQYGTFLCDSERERNELNV------------------------HTRTTSLWS 526
            ...|..|..|...:::.|||.||:.||.|..|                        |.::...::
Frog  1561 QYYLKFLAYHYVSNRFRTFLLDSDCERIEKGVLYEEKGDRRSPQVCRSVWECMERLHKKSPVFYN 1625

  Fly   527 YLNRP---DVLQTFLN------------------PLY-----------EPNAN----------VI 549
            |:..|   :||:.|.:                  |.|           ||..|          :|
Frog  1626 YMFSPEDGEVLRPFSSVWGLRVWDYYTHEALSEGPPYDWELLQGPRHEEPERNDSSAPQTKRKII 1690

  Fly   550 WPS------VAPISL------------------ELWSDLYLRWVIDQRSSVTVMSQIQE--LVTR 588
            |||      |.|.::                  |.|.|.:.:.....|:.|...|:...  |::.
Frog  1691 WPSYNSPARVEPDAITRLLEELHSLEMDLGQVPERWKDTWDKIKAAHRTEVRHESRKSSALLMSS 1755

  Fly   589 EKELRTQALKLRKQAMELGQEVSNLMKSGNDT 620
            .......:|.:..|...:|..::..::||..|
Frog  1756 SVSSHRHSLGVYLQESGVGSTLNLSLESGQST 1787

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5026	NP_001163392.1	PH-GRAM_MTMR9	1..106	CDD:275398
CG5026	NP_001163392.1	Myotub-related	117..511	CDD:284109	123/479 (26%)
sbf1	XP_012813917.1	uDENN	1..86	CDD:214824
		DENN	117..306	CDD:214823
		dDENN	360..428	CDD:129037
		SBF2	538..754	CDD:289132
		PH-GRAM_MTMR5	883..1001	CDD:275417
		Myotub-related	1142..1586	CDD:284109	115/453 (25%)
		PH_Sbf1_hMTMR5	1816..1921	CDD:269941
		PH	1820..1921	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910