DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5653 and paox1

DIOPT Version :9

Sequence 1:	NP_648269.1	Gene:	CG5653 / 39024	FlyBaseID:	FBgn0035943	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001107075.1	Gene:	paox1 / 564675	ZFINID:	ZDB-GENE-081104-436	Length:	490	Species:	Danio rerio

Alignment Length:	518	Identity:	153/518 - (29%)
Similarity:	251/518 - (48%)	Gaps:	86/518 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SSRIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTVYFGDNVIDLGAQWCHG-KQQN 70
            |..|:::||||:|:|||.:|.:..|.:|.:|||.:.:|||:.|...|:..:|.|||:.|| .::|
Zfish     5 SPSIVVVGAGVAGLAAAKKLKEYGFNDVTVLEAAENVGGRVATATLGNACVDTGAQYIHGTSEKN 69

  Fly    71 CVYDMVKDMGILH---ETGD---YYSPIKRVRSNKEVVPHELACRIHDIAVKSMPSGP----HPV 125
            .||.::|  |:|:   |.|:   |.:...:|.:|              .|.::...|.    |..
Zfish    70 PVYCLLK--GLLNQLPEMGEEAFYNNKGHKVNAN--------------FARRAYEHGESFIYHRG 118

  Fly   126 VGSFGTHLTQTFWRKIESELPQVNRDVASEALNTFA---KHESSIIGADNLFEVSVREHIEYHEC 187
            .|:.|..|.:.:..|.:..:.::..|..:...:.||   |.....|||.:|..:|: :..:|:..
Zfish   119 SGNSGKSLGEHYAVKTQGVIERLQEDEKARMQSVFALVGKDMLIDIGASDLHRISL-DSWQYYID 182

  Fly   188 DGDKLLHWGTKGYRRFLRLLMKVSADTPEELGLLEGRIQLDMKVIKIELACPR------------ 240
            .||.:   ...|:...|..|:|  .|.|::..||    :.:::.||.:.:.|.
Zfish   183 MGDSV---NITGFMYQLVDLLK--EDFPKDRLLL----KREVRTIKWDGSFPSPQNEASPEGKVR 238

  Fly   241 --KVILRCQDGDYFEADHVICTVSLGVLQEQHEKLFVPPLPAAKVNAIRSLTLGTVNKLYLEYEK 303
              .|.:.|:||:...|||||.|||||.|:.|...||:|.||..|:..|..|..|.:.|::|.||:
Zfish   239 QYPVCIVCEDGEEILADHVIVTVSLGCLKAQASDLFIPSLPTEKIEVINKLCFGNIAKIFLAYEE 303

  Fly   304 QPLPDGW---VGFFCFWLEEDL---IELRKTEYFWVEGITGVHMITCQPR---MLMAWVNGPHGR 359
            .    .|   ||...|..|:|.   |...|.:  |::.:....::..:.|   :|:.|..|....
Zfish   304 A----FWENDVGSISFIYEDDTPASISTNKMQ--WLKSMQSFSVLRPKERFGNVLIGWCPGEIAD 362

  Fly   360 HMETLSDEKVLEGLYWLFRKFL--TFEIPPPKRFVRSSWFSNPNFRGSWSYR--GVMADERNTGP 420
            .:||::|.::...:....:.|.  :..||.||..:.:.|.||...:||:::.  ||.....:|
Zfish   363 LVETMTDNELSAAVTDHLKMFFGPSANIPQPKSILCTKWRSNKFIKGSYTFLPVGVDGQVMDT-- 425

  Fly   421 WDLESPVLGE---DGHLGLLFAGEASSRNHFSTVHGAVEAGYREADRLIDHY------TSCSV 474
              |..|:.|.   |.||.::|||||:.:..:.||.||:.:|:||||||..||      ||.|:
Zfish   426 --LAQPLEGSQFPDAHLQVMFAGEATMKTLYGTVQGALLSGHREADRLAAHYKDAVASTSASM 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	NAD_binding_8	12..78	CDD:290186	28/66 (42%)
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:279874	142/492 (29%)
paox1	NP_001107075.1	Amino_oxidase	22..471	CDD:279874	136/484 (28%)
paox1	NP_001107075.1	NAD_binding_8	<24..78	CDD:290186	21/55 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583683
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950