Protein Alignment CG5653 and kdm1a

DIOPT Version :9

• Sequence 1: NP_648269.1
• Gene: CG5653 / 39024
• FlyBaseID: FBgn0035943
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001229924.1
• Gene: kdm1a / 558450
• ZFINID: ZDB-GENE-030131-7828
• Length: 833
• Species: Danio rerio
• Alignment Length: 622
• Identity: 149/622 - (23%)
• Similarity: 231/622 - (37%)
• Gaps: 219/622 - (35%)

  Fly     5 RASSRIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTVYFGDNVIDLGAQWCHG--- 66
            :.:.::|:|||||||:||| |.||:...:|.:||:.||:|||:.|...|:.|.||||....|
Zfish   250 KKTGKVIVIGAGVSGLAAA-RQLQSFGMDVTVLESRDRVGGRVATFRKGNYVADLGAMVVTGLGG 313

  Fly    67 -------KQQNCVYDMVKDMGILHE----TGDYYSPI------------KRVRSNKEVVPHELAC 108
                   ||.|.....:|....|:|    .|:..:.:            .|:......:.|:|..
Zfish   314 NPMAVVSKQVNMELAKIKQKCPLYEANGQAGERCTSVPKEKDEMVEQEFNRLLEATSYLSHQLDF 378

  Fly   109 RIHDIAVKSMPSGPHPVVGSFGTHLTQ---TFWRKI---ESELPQVNRDVASEALNTFAKHESSI 167
            ...:....|:......|:.....|:..   ..|:||   :.||    :|:.::.:.|..|
Zfish   379 NFLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEEL----KDLLNKMVTTKEK----- 434

  Fly   168 IGADNLFEVSVRE-HIEYHECD-----GDKLLHWGTKGYRRFLRLLMKVSADTPEELGLLEGRIQ 226
                      |:| |.:|.|..     .|....:..|...|.|..|.|      |...|:|.:::
Zfish   435 ----------VKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCK------EYDELVEMQVK 483

  Fly   227 LDMKVIKIELACPRKVILRC------------------------------QDGDY---------- 251
            |:.::.::|...|..|.|..                              ||.|:
Zfish   484 LEERLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVR 548

  Fly   252 -----------------------------------------------FEADHVICTVSLGVLQEQ 269
                                                           ::.|.|:||:.|||:::|
Zfish   549 NGYSCVPVALAEGLDIKLNTAVRQVRYTSSGCEVIAVNTRSTTQTFIYKCDAVLCTLPLGVMKQQ 613

  Fly   270 HEKL-FVPPLPAAKVNAIRSLTLGTVNKLYLEYEK---QPLPD--GWVG--------FFCFWLEE 320
            ...: ||||||..|..||:.:..|.:||:.|.:::   .|..:  |.||        .|.||
Zfish   614 PPAVQFVPPLPEWKTAAIQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFW--- 675

  Fly   321 DLIELRKTEYFWVEGITGVHMITCQPRMLMAWVNGPHGRHMETLSDE-------KVLEGLYWLFR 378
               .|.|..                  :|:|.:.|.....||.:||:       .:|:|:
Zfish   676 ---NLYKAP------------------ILLALMAGEAAGIMENISDDVIVGRCLAILKGI----- 714

  Fly   379 KFLTFEIPPPKRFVRSSWFSNPNFRGSWSY---------RGVMADERNTGPW--DLESPVLGEDG 432
             |.:..:|.||..|.|.|.::|..|||:||         ..:||.....||.  ....||
Zfish   715 -FGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPAIPGASQPV----- 773

  Fly   433 HLGLLFAGEASSRNHFSTVHGAVEAGYREADRLIDHY 469
             ..|.||||.:.||:.:|||||:.:|.|||.|:.|.:
Zfish   774 -PRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQF 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	NAD_binding_8	12..78	CDD:290186	32/75 (43%)
		Amino_oxidase	17..466	CDD:279874	143/605 (24%)
kdm1a	NP_001229924.1	SWIRM	151..238	CDD:282311
		NAD_binding_8	257..315	CDD:290186	29/58 (50%)
		Amino_oxidase	262..805	CDD:279874	142/604 (24%)
		SKA2	371..>441	CDD:302619	16/88 (18%)
		Prefoldin	393..494	CDD:298833	26/125 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810