Protein Alignment CG5653 and MAOB

DIOPT Version :10

• Sequence 1: NP_648269.1
• Gene: CG5653 / 39024
• FlyBaseID: FBgn0035943
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_000889.3
• Gene: MAOB / 4129
• HGNCID: 6834
• Length: 520
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 133/520 - (25%)
• Similarity: 218/520 - (41%)
• Gaps: 128/520 - (24%)

  Fly     3 KCRASSRIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTV------YFGDNVIDLGA 61
            ||    .::::|.|:||:||| :||.::..||.:|||.||:|||..|:      |     :|||.
Human     4 KC----DVVVVGGGISGMAAA-KLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKY-----VDLGG 58

  Fly    62 QWCHGKQQNCVYDMVKDMGILHETGDYYSPIKRVRSNKEVVPHELACRIHDIAVKSMP-SGPHPV 125
            .:. |..||.:..:.|::|:  ||   |.            .:|:...||.:..||.| .||.|.
Human    59 SYV-GPTQNRILRLAKELGL--ET---YK------------VNEVERLIHHVKGKSYPFRGPFPP 105

  Fly   126 VGSFGTHLT-QTFWRKIESELPQVNRDVASEA------------------LNTFAKHESS----- 166
            |.:..|:|. ..|||.::    .:.|::.|:|                  |:.....||:
Human   106 VWNPITYLDHNNFWRTMD----DMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLAT 166

  Fly   167 -----IIGADNLFEVSVREHIEY-HECDGDKLLHWGTKG--YRRFLRLLMKVSADTPEELGLLEG 223
                 .:.|:. .|||....:.| .:|.|...:...|.|  .|:|:....:||   ...:.||..
Human   167 LFVNLCVTAET-HEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVS---ERIMDLLGD 227

  Fly   224 RIQLDMKVIKIELACPRKVILRCQDGDYFEADHVICTV--SLGVLQEQHEKL-FVPPLPAAKVNA 285
            |::|:..||.|: .....|::...:.:.:||.:||..:  :||:      |: |.||||..:...
Human   228 RVKLERPVIYID-QTRENVLVETLNHEMYEAKYVISAIPPTLGM------KIHFNPPLPMMRNQM 285

  Fly   286 IRSLTLGTVNKLYLEYEKQPLPDGWVGFFCFWLEEDLIELRKTEYFWVEGITGVH------MITC 344
            |..:.||:|.|. :.|.|:|          ||        ||.:|.....|.|..      :...
Human   286 ITRVPLGSVIKC-IVYYKEP----------FW--------RKKDYCGTMIIDGEEAPVAYTLDDT 331

  Fly   345 QPR----MLMAWVNGPHGRHMETLSDEKVLEGLYWLFRKFL-TFEIPPPKRFVRSSWFSNPNFRG 404
            :|.    .:|.::.....|.:..|:.|:.|:.|..|:.|.| :.|...|..:...:|.......|
Human   332 KPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGG 396

  Fly   405 SWSY---RGVMADERNTGPWDLESPVLGEDGHLGLLFAGEASSRNHFSTVHGAVEAGYREADRLI 466
            .::.   .|::......    |..||   |   .:.|||..::.:....:.||||||.|.|..::
Human   397 CYTTYFPPGILTQYGRV----LRQPV---D---RIYFAGTETATHWSGYMEGAVEAGERAAREIL 451

  Fly   467  466
            Human   452  451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:396255	129/504 (26%)
MAOB	NP_000889.3	YobN	14..455	CDD:440844	129/506 (25%)