DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5653 and smox

DIOPT Version :9

Sequence 1:	NP_648269.1	Gene:	CG5653 / 39024	FlyBaseID:	FBgn0035943	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001315115.1	Gene:	smox / 387290	ZFINID:	ZDB-GENE-031201-3	Length:	539	Species:	Danio rerio

Alignment Length:	574	Identity:	171/574 - (29%)
Similarity:	253/574 - (44%)	Gaps:	143/574 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEKCRASS-----------------RIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRIN 48
            |:.|..||                 ||::||||::|:||...||:|.|.||.:|||.||||||:.
Zfish     1 MQSCEISSDSTDDPLSSALHGHRQPRIVVIGAGLAGLAATKTLLENGFTNVTVLEASDRIGGRVQ 65

  Fly    49 TVYFGDNVIDLGAQWCHGKQQNCVYDMVKDMGILHETGDYYSPIKRV------------RSNKEV 101
            ::..|...::|||.|.||...|.||.:.:|.|:|..|.:....:.|:            .:|.:.
Zfish    66 SIQHGKTTLELGATWIHGANGNPVYHLAEDNGLLEHTTEEERSVGRISLYAKNGVAHYQTNNGKR 130

  Fly   102 VPHELACRIHDIAVKSMPSGPHPVVGSFGTHLTQTFWR-------KIESELPQVNRDVA------ 153
            :|.:|.....|:..:..             .|||.|::       :.::.:....|||.
Zfish   131 IPKDLVEEFSDLYNEVY-------------ELTQEFFQNGKPVGAESQNSVGIFTRDVVRKKIML 182

  Fly   154 ----SEA--------LNTFAKHESSIIGADNLFEVSVREHIEYHECDGDKLLHWGTKGYRRFLRL 206
                ||:        |..:.|.||....:.|:.|||:.|..|:.|..|..  |....|   |:::
Zfish   183 DPYDSESIRKLKLSMLQQYLKVESCESSSPNMDEVSLSEFGEWTEIPGAH--HVIPTG---FIKV 242

  Fly   207 LMKVSADTPEELGLLEGRIQLDMKVIKIELAC---------------------PRKVILRCQDGD 250
            :..::.|.|..:      :.|...|.::...|                     |..|.:.|:||:
Zfish   243 VEILAQDIPSCV------LHLSKPVRRVHWNCSSQDAEEFGDQVDHNQDQRPSPSPVCVECEDGE 301

  Fly   251 YFEADHVICTVSLGVLQEQHEKLFVPPLPAAKVNAIRSLTLGTVNKLYLEYEKQPLPDGWVGFFC 315
            ...|||||.|.|||||::.|:.||.|.||..|..||:.|.:.|.:|::||:.:.
Zfish   302 RLLADHVILTASLGVLKKAHKTLFSPGLPQDKAQAIQKLGISTTDKIFLEFAEP----------- 355

  Fly   316 FW---------LEEDLIELRKTEY---FWVEGITGVHMITCQPR---MLMAWVNGPHGRHMETLS 365
            ||         :.||..:|....|   .|...|....::....|   ||..|:.|.....||...
Zfish   356 FWSPECNSIQFVWEDEAQLESQAYPEELWYRKICSFDVLYPPERYGHMLSGWICGEEALRMERCD 420

  Fly   366 DEKVLEGLYWLFRKFL-TFEIPPPKRFVRSSWFSNPNFRGSWSYRGVMADERNTGPWDLESPVLG 429
            ||.|.|....|.|:|. ...||.|:|.:||||.|||..|||:|:..|.:..|     |:|.  |.
Zfish   421 DETVAEICTELLRQFTGNQNIPKPRRILRSSWGSNPYIRGSYSFTRVGSSGR-----DVEK--LA 478

  Fly   430 ED---------GHLGLLFAGEASSRNHFSTVHGAVEAGYREADRLIDHYT-SCS 473
            |.         ..|.:||||||:.|.::||.|||:.:|.|||:||::.|. ||:
Zfish   479 EPLPYIKNTKAPPLQVLFAGEATHRKYYSTTHGALLSGQREANRLMELYQYSCA 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	NAD_binding_8	12..78	CDD:290186	32/65 (49%)
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:279874	157/531 (30%)
smox	NP_001315115.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583687
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	1	1.100	-	-	O	PTHR10742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.750