DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5653 and zgc:66484

DIOPT Version :9

Sequence 1:	NP_648269.1	Gene:	CG5653 / 39024	FlyBaseID:	FBgn0035943	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_005167974.1	Gene:	zgc:66484 / 327557	ZFINID:	ZDB-GENE-030131-5768	Length:	524	Species:	Danio rerio

Alignment Length:	517	Identity:	157/517 - (30%)
Similarity:	253/517 - (48%)	Gaps:	82/517 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SSRIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTVY-FGDNVIDLGAQWCHGKQQN 70
            ::::::||:|.:|:|||::|::..|::|.:|||::|:|||::|.. |.:|:|::||.|.||::.|
Zfish    36 NAKVLVIGSGFAGLAAASKLIEAGFEDVLVLEAKERVGGRVHTTKPFTENIIEVGANWIHGQKGN 100

  Fly    71 CVYDMVKDMGILHE---------------TGDYY-----SPIKRVRSNKEVVPHELA--CRIHDI 113
            .:|.:.|:..:|.|               ..||:     .|:.     |.||....|  .::.|.
Zfish   101 PLYKIAKEKNLLSEGPSAMKNMCLPHSVSPRDYFFNEDGKPVP-----KSVVDQVCARFSKLTDK 160

  Fly   114 AVKSMPSGPHP--VVGSF------GTHLTQTFWRKIESELPQVNRDVASEALNTFAKHESSIIGA 170
            |......|.:.  .:|::      ||.|::|              :.|.:......:.|.:....
Zfish   161 AFDDELDGKYRKLTLGAYLDDAFGGTELSKT--------------EDARQVYEWCKRVECTDEAC 211

  Fly   171 DNLFEVSVREHIEYHECDGDKLLHWGTKGYRRFLRLLMKVSADTPEELGLLEGRIQLDMKVIKIE 235
            .:|:|:|..:...|.|.:|......|..||:..|.:|::   |.|.|    ..|....:|.|:.:
Zfish   212 SSLYEISASQLSNYTELEGGFFNTLGPGGYQAILDVLLR---DVPSE----AVRCNAPVKTIRWD 269

  Fly   236 LA---------CPRKVILRCQDGDYFEADHVICTVSLGVLQEQHEKLFVPPLPAAKVNAIRSLTL 291
            |.         .|.:|:  |::|..|||||||.|||||||:|..:.:|.|.||..|::||..|..
Zfish   270 LVKEGQSEEEDHPVQVV--CENGQTFEADHVIVTVSLGVLKEHAKTMFDPTLPEKKLSAINDLGF 332

  Fly   292 GTVNKLYLEYEKQPLPDGWVGFFCFWLE--------EDLIELRKTEYFWVEGITGVHMITCQPRM 348
            |.|||::|.:||...||...|....|.|        |||.|....:..|.:.|||...:...|..
Zfish   333 GIVNKIFLFFEKSFWPDDCAGVQLVWKEGPEDKDVYEDLSEGEDWKQTWFKKITGFDTVARHPTA 397

  Fly   349 LMAWVNGPHGRHMETLSDEKVLEGLYWLFRKFLTFEIPPPKRFVRSSWFSNPNFRGSWSY----- 408
            |..|:.|....:||:|.|.::.|....|.|....:.:|...:.:.|.|.|:|..|||:::
Zfish   398 LCGWITGREALYMESLQDREIQEVCVRLLRSSTGWPVPEVSKTLISRWGSDPQVRGSYTFVPDGV 462

  Fly   409 RGVMADERNTGPWDLESPVLGEDGHLGLLFAGEASSRNHFSTVHGAVEAGYREADRLIDHYT 470
            .||.|.:....|...:....|.. :|.:||||||:..|.::|.|||..:|.|||:|||.:|:
Zfish   463 DGVEAHKALASPLPPKHRSRGRK-NLQVLFAGEATHVNFYTTTHGAYLSGQREAERLISYYS 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	NAD_binding_8	12..78	CDD:290186	28/66 (42%)
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:279874	151/501 (30%)
zgc:66484	XP_005167974.1	PLN02568	37..522	CDD:215308	156/513 (30%)
zgc:66484	XP_005167974.1	NAD_binding_8	41..101	CDD:290186	26/59 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583695
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0685
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H77187
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375579at33208
OrthoFinder	1	1.000	-	-		FOG0000632
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102123
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X429
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.650