Protein Alignment CG5653 and IL4I1

DIOPT Version :10

• Sequence 1: NP_648269.1
• Gene: CG5653 / 39024
• FlyBaseID: FBgn0035943
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_758962.1
• Gene: IL4I1 / 259307
• HGNCID: 19094
• Length: 589
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 115/559 - (20%)
• Similarity: 184/559 - (32%)
• Gaps: 223/559 - (39%)

  Fly     9 RIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRI------NTVYFGDNVIDLGA------ 61
            |:|::||||:|:.|| ::|.:....|.||||::||||||      ||.:.|    :|||
Human    83 RVIVVGAGVAGLVAA-KVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIG----ELGAMRMPSS 142

  Fly    62 -----QWCHGKQQNCV----YDMVKDMGILHETGDYYSPIKRVRSNK---EVVPHELACRIHDIA 114
                 :.|.|...|..    ||.           :.::.:..|:...   |.||.:|.     .|
Human   143 HRILHKLCQGLGLNLTKFTQYDK-----------NTWTEVHEVKLRNYVVEKVPEKLG-----YA 191

  Fly   115 VKSMPSGPHPVVGSFGTHLTQTFWRKIESELPQVNRDVAS----EALNTFAKHE----------- 164
            ::....|          |..:..:   :..|.|..:|:.:    :|:..|.:|.
Human   192 LRPQEKG----------HSPEDIY---QMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNL 243

  Fly   165 --------SSIIGADNLFEVSVREHIEYHECDGDKLLHWGTKGYRRFL---RLLMKVSADTPEEL 218
                    ..::..|..|.:|..|.:..|.|..|:|      .|.|.:   .||.:..      |
Human   244 SRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRL------QYSRIVGGWDLLPRAL------L 296

  Fly   219 GLLEGRIQLDMKV-----------IKIELACPRKVILRCQDGDYFEADHVICTVSLGVLQEQHEK 272
            ..|.|.:.|:..|           ::||.:.|.:.:      ...:||.|:.|.|...::   ..
Human   297 SSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNL------KVLKADVVLLTASGPAVK---RI 352

  Fly   273 LFVPPLPAAKVNAIRSLTLGTVNKLYLEYEKQPLPDGWVGFFCFWLEEDLIELRKTEYFWVEGIT 337
            .|.||||.....|:|.|......|::|.:.:.           ||.||.              |.
Human   353 TFSPPLPRHMQEALRRLHYVPATKVFLSFRRP-----------FWREEH--------------IE 392

  Fly   338 GVHMITCQPRMLMAWVNGPHGRHMETLSDEKVLEGLYWLFRKFLTFEIPPPKR----FVRSSW-- 396
            |.|..|.:|..::.:                                 |||:.    ....:|
Human   393 GGHSNTDRPSRMIFY---------------------------------PPPREGALLLASYTWSD 424

  Fly   397 -----------------------FSNPNFRGSWSYRGVM----ADERNTGPWDLESPVLGED--- 431
                                   ...|..|..|...||:    .|:.:.|.:.::.|.|.:.
Human   425 AAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPPALWQTEKD 489

  Fly   432 ------GHLGLLFAGEASSRNHFSTVHGAVEAGYREADR 464
                  |.  :.||||     |.:..||.||...:.|.|
Human   490 DWTVPYGR--IYFAGE-----HTAYPHGWVETAVKSALR 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:396255	110/551 (20%)
IL4I1	NP_758962.1	YobN	75..529	CDD:440844	115/559 (21%)