DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5653 and maoa

DIOPT Version :9

Sequence 1:	NP_648269.1	Gene:	CG5653 / 39024	FlyBaseID:	FBgn0035943	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_012811952.1	Gene:	maoa / 100145726	XenbaseID:	XB-GENE-5749883	Length:	521	Species:	Xenopus tropicalis

Alignment Length:	504	Identity:	115/504 - (22%)
Similarity:	207/504 - (41%)	Gaps:	106/504 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTV------YFGDNVIDLGAQWCHGKQ 68
            ::::|.|:||::|| :||..:..:|.:|||.||:|||.:||      |     :|||..:. |..
Frog     7 VVVVGGGISGLSAA-KLLSESGISVVVLEARDRVGGRTHTVRNKQVKY-----VDLGGAYV-GPT 64

  Fly    69 QNCVYDMVKDMGILHETGDYYSPIKRVRSNKEVVPHELA-----CRIHDIAVKSMPSGPHPVVGS 128
            ||.:..|.||:|:  ||       .:|..|..::.|...     |       .:.|...:|.|..
Frog    65 QNRLLRMAKDLGL--ET-------YKVNLNGRLIQHTKGKSYTFC-------GAFPPAYNPFVYL 113

  Fly   129 FGTHLTQTF--WRK-IESELPQ----------------VNRDVASEALNTFAKHESSIIGADNLF 174
            ...::.:|.  |.| |.:|.|.                :|....::....||....::|......
Frog   114 DYNNVMRTMDQWAKEIPAEAPWKAPHAAEWDRMSMMEFINNTCWTQTGRRFATIFVNLIVTAETH 178

  Fly   175 EVSVREHIEYHECDGDKLLHWGTKG---YRRFLRLLMKVSADTPEELGLLEGRIQLDMKVIKIEL 236
            ::|....:.|.:..|.....:.|:.   .|:|:....::|....|.   |:||:.|:..||||:.
Frog   179 QISTLWFLWYIKLCGGTTRAFSTENGGQERKFVGGSGQISERIMER---LQGRVMLESPVIKIDQ 240

  Fly   237 ACPRKVILRCQDGDYFEADHVICTVSLGVLQEQHEKLFVPPLPAAKVNAIRSLTLGTVNKLYLEY 301
            :.| .||:...:.:.|||.::|..:...:..:.|   |.|.|||.:...|:.|.:|:|.|..:.|
Frog   241 SGP-CVIVETLNHETFEAKYIISAIPPVLTTKIH---FEPELPAIRNQLIQRLPMGSVIKCMVYY 301

  Fly   302 EKQPLPDGWVGFFCFWLEED-----LIELRKTEYFWVEGITGVHMITCQP----RMLMAWVNGPH 357
            ::           .||.:.|     ::|...|.       .|..:...:|    ..::.::....
Frog   302 KE-----------AFWRKMDICGCMIMEDDDTP-------IGFTLDDTKPDGTEPAIIGFILSRK 348

  Fly   358 GRHMETLSDEKVLEGLYWLFRKFL-TFEIPPPKRFVRSSWFSNPNFRG----SWSYRGVMADERN 417
            ...|..|:.|:....:...:.|.: |.|...|..:....| |...:.|    ::...|:|....:
Frog   349 ATLMTNLTKEERKRKICEYYAKVMGTDEALHPVHYEEKDW-SKEQYSGGCYTAYFPPGIMTQYGS 412

  Fly   418 TGPWDLESPVLGEDGHLGLLFAGEASSRNHFSTVHGAVEAGYREADRLI 466
            .    :..|| |:     :.|||..::......:.||::||.|.|..::
Frog   413 V----IRKPV-GK-----MYFAGTETATEWSGYMEGAIQAGERAAREIM 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5653	NP_648269.1	NAD_binding_8	12..78	CDD:290186	27/71 (38%)
CG5653	NP_648269.1	Amino_oxidase	17..466	CDD:279874	113/495 (23%)
maoa	XP_012811952.1	YobN	15..452	CDD:224152	113/496 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910