Protein Alignment ValRS-m and valS

DIOPT Version :10

• Sequence 1: NP_648268.1
• Gene: ValRS-m / 39023
• FlyBaseID: FBgn0035942
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_418679.1
• Gene: valS / 948785
• ECOCYCID: EG11067
• Length: 951
• Species: Escherichia coli
• Alignment Length: 1003
• Identity: 345/1003 - (34%)
• Similarity: 521/1003 - (51%)
• Gaps: 124/1003 - (12%)

  Fly    43 YQPQPVEN---AYWERE-HRQANLPKASASSCKRGTYRMLLPPPNVTGNLHLGHALMATVQDVIA 103
            |.||.:|.   .:||:: :.:.|..::..|.|      :::|||||||:||:|||...|:.|.:.
E. coli     5 YNPQDIEQPLYEHWEKQGYFKPNGDESQESFC------IMIPPPNVTGSLHMGHAFQQTIMDTMI 63

  Fly   104 RQREQLGYQVDWVPGTDHAGIATQVVVERTIAASQAKTRHELGRSAFLDEVWRWKAEKGAGIVQD 168
            |.:...|....|..||||||||||:||||.|||.:.||||:.||.||:|::|.||||.|..|.:.
E. coli    64 RYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQ 128

  Fly   169 LRQLGCKLNWQREYFTMDEQQAHAVNVAFERLFEEGLIQRRNSVVNWCTALRSAISDIEVDSVEI 233
            :|:||..::|:||.|||||..::||...|.||::|.||.|...:|||...||:||||:||::.|.
E. coli   129 MRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRES 193

  Fly   234 TEPVEISVPGYDHKVLFGRMYDFAYHVVDGEALPDGSVEEIVVSTTRPETILGDVAVAVHPLDPR 298
            .                |.|:...|.:.||....||. :.:||:||||||:|||..|||:|.|||
E. coli   194 K----------------GSMWHIRYPLADGAKTADGK-DYLVVATTRPETLLGDTGVAVNPEDPR 241

  Fly   299 Y----AKYRNIDQVKLKHPFRDDTIPLVFDITVDQEFGTGAVKITPAHDKFDFELATRHKL---- 355
            |    .||..:       |..:..||:|.|...|.|.|||.||||||||..|:|:..||.|
E. coli   242 YKDLIGKYVIL-------PLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMIN 299

  Fly   356 ---------EPRQVFTETGLVVDAYS-----EYKGIPRFEARDLIVNRLEEMDLLRQVRSHTMQL 406
                     |..|||...|...|.||     |::.:.||.||..:|..::.:.||.:::.|.:.:
E. coli   300 ILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTV 364

  Fly   407 PICSRSKDVIEYMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETEWERWLQDSRDWCISRQL 471
            |...|...|||.|:..||:::...|||.|:..:.:|.:|.:|..:|..:..|::|.:||||||||
E. coli   365 PYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQL 429

  Fly   472 WWGHQVPAYEVIDSQGNSQWVAALDEKTARQKAMRLIGSEEFTLKRDPDVLDTWFSSSLLPFSTA 536
            ||||::||:  .|..|| .:|...:::..::..:    ..:..|::|.|||||||||:|..|||.
E. coli   430 WWGHRIPAW--YDEAGN-VYVGRNEDEVRKENNL----GADVVLRQDEDVLDTWFSSALWTFSTL 487

  Fly   537 GWPE--ESYKERYPLDIMQTGHDIIFFWVARMMMLGLKL------TGEAPFQRILLNGIVCDAHG 593
            ||||  ::.::.:|..:|.:|.||||||:|||:|:.:..      ..:.||..:.:.|::.|..|
E. coli   488 GWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEG 552

  Fly   594 RKMSKSIGNIVAPQQVVQGASLESLKAGLEQSCEAGIITPSELKASTIGMTQ-MFPNGIQECGTD 657
            :|||||.||::.|..:|.|.||..|   ||:  ..|.:...:|.......|: .|||||:..|||
E. coli   553 QKMSKSKGNVIDPLDMVDGISLPEL---LEK--RTGNMMQPQLADKIRKRTEKQFPNGIEPHGTD 612

  Fly   658 ALRFTLMSHNIKSHFISFDVNACHTNKLFLNKVWQAMRFTLGSAKGLGISLHQFETLEGVNLGLW 722
            ||||||.:.......|::|:......:.|.||:|.|.||.|.:.:|.....:..|    :.|.|.
E. coli   613 ALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGE----MTLSLA 673

  Fly   723 DRWIVGRLAETLSVCSQSYSNYNFHLATAALKTFFYQYLCDTYLETTKPAI-GNRSADAYIHVGT 786
            ||||:....:|:....::..::.|.:|...|..|.:...||.|||.|||.: |...|:......|
E. coli   674 DRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHT 738

  Fly   787 LTACLSWGLQAMAPYAPFVASELLQHVPL-------NIELK-LSDYKDEKLEE----EVNEIVNI 839
            |...|...|:...|..||:...:.|.|.:       .|.|: ...|...:::|    :...:...
E. coli   739 LVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQA 803

  Fly   840 CHNVRQVKSRNEISKRHHPQLSLFAQNTDSEGVLRRHLPQIKVLSRCEDVELELFDESSKISKQL 904
            ...||.:::...|:.....:|.|...:.|:|..:..:...::.|:|.|.:.:...|:...:|.
E. coli   804 IVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSV-- 866

  Fly   905 SYFSTAGALCSFGLKLSDGLD-LTP-----EKRDEMQKANAKKLKKLVTELQRYRMRLDNEAFQL 963
                         .|:.||.: |.|     .|.||:.:. ||::.|:..|:.|...:|.||.|..
E. coli   867 -------------TKIIDGAELLIPMAGLINKEDELARL-AKEVAKIEGEISRIENKLANEGFVA 917

  Fly   964 MAD--------KKVKSHFENKVKELEAE 983
            .|.        :|::.:.|.|.|.:|.:
E. coli   918 RAPEAVIAKEREKLEGYAEAKAKLIEQQ 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ValRS-m	NP_648268.1	PTZ00419	23..989	CDD:240411	345/1003 (34%)
valS	NP_418679.1	ValS	1..949	CDD:440291	345/1003 (34%)