Protein Alignment ValRS-m and vrs2

DIOPT Version :10

• Sequence 1: NP_648268.1
• Gene: ValRS-m / 39023
• FlyBaseID: FBgn0035942
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_593819.1
• Gene: vrs2 / 2543603
• PomBaseID: SPAC4A8.08C
• Length: 950
• Species: Schizosaccharomyces pombe
• Alignment Length: 995
• Identity: 321/995 - (32%)
• Similarity: 516/995 - (51%)
• Gaps: 128/995 - (12%)

  Fly    35 NELPLAAGYQPQPVENAYWEREHRQANLPKASASSCKRGTYRMLLPPPNVTGNLHLGHALMATVQ 99
            |.:.:.|.:....:::. |....:..:.||  ..|.:...:.:||||||:||.||:||||..|:|
pombe    23 NYIHIEAPFDIAAIQDG-WNIIRKHIHYPK--PKSIEAPMFPILLPPPNITGKLHIGHALTITIQ 84

  Fly   100 DVIARQREQLGYQVDWVPGTDHAGIATQVVVERTIAASQAKTRHELGRSAFLDEVWRWKAEKGAG 164
            |.:||.....||:|.:.|||||||||||.|||:.: ..:...|::|.:...|..:..|:.:....
pombe    85 DALARFYAMHGYKVSFRPGTDHAGIATQSVVEKYL-QKKGVYRNQLSKDELLSSIHSWQVKYQKS 148

  Fly   165 IVQDLRQLGCKLNWQREYFTMDEQQAHAVNVAFERLFEEGLIQRRNSVVNWCTALRSAISDIEVD 229
            |:..|:......:|...::|||:.::.|||.||..||..|||.|.|..||||..|.||:|||||:
pombe   149 IINQLKSFEAIFDWDNIFYTMDQNRSEAVNEAFISLFNAGLIYRANRFVNWCPKLESAVSDIEVE 213

  Fly   230 SVEITEPVEISVPGYDHKVLFGRMYDFAYHVVDGEALPDGS-VEEIVVSTTRPETILGDVAVAVH 293
            |.:|.:||...|.  :..|.||.:|:.:|.:       :|| .|::.|||||||||.||.|:||.
pombe   214 SQQINKPVTKYVD--NTPVEFGWLYEISYQL-------EGSDNEQLNVSTTRPETIFGDRAIAVS 269

  Fly   294 PLDPRYAKYRNIDQVKLKHPFRDD-TIPLVFDITVDQEFGTGAVKITPAHDKFDFELATRHKLEP 357
            |.|.||.||  :.:. :|||..|| .||::.|..||:.||||.:||||.|...|:|:|.||.::.
pombe   270 PHDERYKKY--VGRF-VKHPLIDDLLIPVICDNAVDRHFGTGVLKITPMHSIVDYEIAKRHNIDC 331

  Fly   358 RQVFTETGLVVDAYSEYKGIPRFEARDLIVNRLEEMDLLRQVRSHTMQLPICSRSKDVIEYMILP 422
            ..:..::|.:::...|..|:.|.:||..||..|::.:.|.:...|::.|.:|||:.||||.:::|
pombe   332 VSIMDKSGNLINCSKEVNGMNRLKARSKIVRLLQQRNRLVEQVPHSLILSVCSRTGDVIEPVMVP 396

  Fly   423 QWFLKCKDLAKDALSELHSGRLQILPPNFETEWERWLQDSRDWCISRQLWWGHQVPAYEVIDSQG 487
            ||:|....|.|:.|..  |.:|:::|.....||:.|.:...|||||||:|||||:|.:::::
pombe   397 QWYLSVDSLKKEVLKS--SNKLKLVPSLARKEWDSWFKKMGDWCISRQIWWGHQIPVWKILE--- 456

  Fly   488 NSQWVAALDEKTARQKAMRL-IGSEEFTLKRDPDVLDTWFSSSLLPFSTAGWPEESYKERYPLDI 551
            ..:|:||.:    .:||::| :|.   ::.:|.|||||||||:|||.|..|||:.  |:..||..
pombe   457 EDKWIAAPN----YEKALQLSVGK---SVSQDSDVLDTWFSSALLPLSAFGWPKS--KDIQPLPF 512

  Fly   552 MQTGHDIIFFWVARMMMLGLKLTGEAPFQRILLNGIVCDAHGRKMSKSIGNIVAPQQVVQGASLE 616
            :::|.||:|||:|||.:|....:.|.||:.|:|:.:|.|:.|||||||:||::.|..::.|.:||
pombe   513 IESGQDILFFWIARMALLCKYFSNELPFKEIILHPLVRDSEGRKMSKSLGNVIDPMDIINGVTLE 577

  Fly   617 SLKAGLEQSCEAGIITPSELKASTIGMTQMFPNGIQECGTDALRFTL---MSHNIKSHFISFDVN 678
            ::|..|.:    |.:..||:..|:..|.:.|||||...|.|..|:.|   :.|..:   |..|:|
pombe   578 NMKKALLE----GNLPISEVHKSSKQMEKAFPNGIPAQGIDIFRYGLFLCLHHEQR---ILLDMN 635

  Fly   679 ACHTNKLFLNKVWQAMRF-----------TLGSAKGLGISLHQFETLEGVNLGLWDRWIVGRLAE 732
            :......|::|:|...|:           .|..::...|||.:..|             ..:|..
pombe   636 SFSDAHRFVSKLWNLARYFNQYKDKENPLKLTDSQRQRISLLKMAT-------------YSKLHH 687

  Fly   733 TLSVCSQSYSNYNFHLATAALKTFFYQYLCDTYLETTKPAIGNRSADAYIHVGTLTACLSWGLQA 797
            .:....:|:....|..|...:|.|....|...|:|.|:..:.:..:.||......:..|...|:.
pombe   688 AVEGVKESFEQRKFFNAADIMKNFLLNDLSSVYVELTRFDVKDSKSSAYEVYRVFSDILHIFLKL 752

  Fly   798 MAPYAPFVASELLQHVPLNIELKLSDY-------------KDEKLEEEVNEIVNICHNVRQVKS- 848
            :.|..|.::..:| |..:..|.|.|::             .|.:.|..|....::...:|:::|
pombe   753 IHPIVPCISGVML-HSKIIPERKNSEFLSFPTSQQECLLVHDNQAEVVVQNAYDVLIQLRKLESP 816

  Fly   849 RNEISKRHH--------PQLSLF----AQNTDSEGVLRRHLPQIKVLSRCEDVELELFDESSKIS 901
            .|:...|.|        ..|..|    .|:|:           :|:.|..::..::|....:.|.
pombe   817 LNKSPSREHTVYISTSLEPLKYFYDAIEQSTN-----------LKLKSISQEDTIDLMRNQTFIL 870

  Fly   902 KQLSYFSTAGALCSFGLKLSDGLDLTPEKRDEMQKANAKKLKKLVTELQRYRMRLDNEAFQLMAD 966
            .::|               ||.:.|.|:|   :..:..|||:|.:.:||:   :||.......:.
pombe   871 SRIS---------------SDTILLVPKK---LYPSKRKKLRKNLDDLQK---KLDKIQHTTSSS 914

  Fly   967 --KKVKSHFENKVKELEAEI 984
              :|..|:.:.|..||:.:|
pombe   915 GYEKAPSYIKLKNCELQKDI 934

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ValRS-m	NP_648268.1	PTZ00419	23..989	CDD:240411	321/995 (32%)
vrs2	NP_593819.1	PTZ00419	18..945	CDD:240411	321/995 (32%)