Protein Alignment ValRS-m and vrs1

DIOPT Version :10

• Sequence 1: NP_648268.1
• Gene: ValRS-m / 39023
• FlyBaseID: FBgn0035942
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: NP_595435.1
• Gene: vrs1 / 2540197
• PomBaseID: SPBC1709.02C
• Length: 980
• Species: Schizosaccharomyces pombe
• Alignment Length: 915
• Identity: 353/915 - (38%)
• Similarity: 510/915 - (55%)
• Gaps: 76/915 - (8%)

  Fly    38 PLAAGYQPQPVENA---------YWEREHRQANLPKASASSCKRGTYRMLLPPPNVTGNLHLGHA 93
            |....|.|:.||:|         ::|.|......||      |.|.:.:..|||||||.||:|||
pombe    92 PALKSYNPKAVESAWYDWWVKSGFFEPEFGPDGKPK------KEGVFVITSPPPNVTGALHIGHA 150

  Fly    94 LMATVQDVIARQREQLGYQVDWVPGTDHAGIATQVVVERTIAASQAKTRHELGRSAFLDEVWRWK 158
            |...:||.:||....||..|.::.|.||||::||.|||:.:..:|.||||:..|..|:|.||.||
pombe   151 LTIAIQDSLARWNRMLGKTVLFLGGFDHAGLSTQSVVEKKLWYTQKKTRHDYPRDKFVDIVWEWK 215

  Fly   159 AEKGAGIVQDLRQLGCKLNWQREYFTMDEQQAHAVNVAFERLFEEGLIQRRNSVVNWCTALRSAI 223
            .|....|...:.:||...:|.||.|||||..:.||...|.||.||.:|.|.|.:|||||||::.:
pombe   216 EEYHNRIKNQMSRLGGSFDWTREAFTMDENLSRAVVETFVRLHEENIIYRANRLVNWCTALQTTL 280

  Fly   224 SDIEVDSVEITEPVEISVPGYDHKVLFGRMYDFAYHVVDGEALPDGSVEEIVVSTTRPETILGDV 288
            |::||::|::.....:.|||||..|..|.:...||.|       :||.|.||::||||||:|||.
pombe   281 SNLEVENVDVPGRTLLKVPGYDEPVEVGVLTSIAYAV-------EGSDERIVIATTRPETLLGDT 338

  Fly   289 AVAVHPLDPRYAKYRNIDQVKLKHPFRDDTIPLVF-DITVDQEFGTGAVKITPAHDKFDFELATR 352
            ||||||.|||   |:::....:||||.:.:||::. ||.||.||||||||||||||..|:|:..|
pombe   339 AVAVHPQDPR---YKHLHGKFVKHPFCNRSIPIICDDIIVDMEFGTGAVKITPAHDPNDYEVGKR 400

  Fly   353 HKLEPRQVFTETGLVVDAYSEYKGIPRFEARDLIVNRLEEMDLLRQVRSHTMQLPICSRSKDVIE 417
            |.||...:||:.||:.:...|:.|:.||.||..:|.||:|:.|....:.:.|.:|:|.::.|:||
pombe   401 HNLEFINIFTDDGLLNENCGEFAGMKRFTARVKVVERLKELGLFVGTKENPMVIPLCGKTSDIIE 465

  Fly   418 YMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETEWERWLQDSRDWCISRQLWWGHQVPAYEV 482
            .::.|||::..|::|..|...:.||.::|.|.....|:.||:::.:||||||||||||::|||.|
pombe   466 PVMKPQWWVNQKEMAAAAAEVVKSGEIEIAPDMSRREFIRWMENIQDWCISRQLWWGHRIPAYFV 530

  Fly   483 ----IDSQGNSQ---WVAALDEKTARQKAMRLIGSEEFTLKRDPDVLDTWFSSSLLPFSTAGWPE 540
                ..||..|:   ||.....:.|.:||......:.|||::|.|||||||||.|.||||.|||:
pombe   531 NLADEPSQDRSEGRYWVTGRTLEQAEEKAKAAFPGKSFTLEQDEDVLDTWFSSGLWPFSTLGWPK 595

  Fly   541 ES--YKERYPLDIMQTGHDIIFFWVARMMMLGLKLTGEAPFQRILLNGIVCDAHGRKMSKSIGNI 603
            ::  |:..||..:|:||.||:|||:|||:||||||||:.||:|:..:.:|.||.|||||||:||:
pombe   596 DTSDYENFYPTTLMETGWDILFFWIARMVMLGLKLTGKIPFKRVFCHALVRDAQGRKMSKSLGNV 660

  Fly   604 VAPQQVVQGASLESLKAGLEQSCEAGIITPSELKASTIGMTQMFPNGIQECGTDALRFTLMSHNI 668
            |.|..|::|.||::    |......|.:...|::.:..|....:|.||.:||||||||||.|...
pombe   661 VDPIDVIEGISLQA----LHDKLLVGNLDSREVEKAKKGQRLSYPKGIPQCGTDALRFTLCSLTT 721

  Fly   669 KSHFISFDVNACHTNKLFLNKVWQAMRFTLGSAKGLGISLHQFET--LEGVNLGLWDRWIVGRLA 731
            ....::.|:......:.|.||::.|.:|.||.   ||.:....:|  |.| |..|.::||..||.
pombe   722 GGRDLNLDILRVEGYRKFCNKLYNATKFALGR---LGSNFVPNKTADLTG-NESLVEKWIFHRLN 782

  Fly   732 ETLSVCSQSYSNYNFHLATAALKTFFYQYLCDTYLETTK------PAIGNRSADAYIHVGTLTAC 790
            ...:..:::....||..||:|:..|:...|||.|:|.:|      ..:...||..     ||...
pombe   783 IAAAAMNKNMEEMNFLQATSAVHQFWLYELCDVYIENSKYLLSDGTEVQQESAKQ-----TLYTV 842

  Fly   791 LSWGLQAMAPYAPFVASELLQHVPLN------------IELKLSDYKDEKLEEEVNEIVNICHNV 843
            |...|:.|.|:.|:|..|:.|.:|..            ..::..||.:|...:....|:.:.|:.
pombe   843 LDNALRLMHPFMPYVTEEMWQRLPRRPGDKTQTIVKAAFPVERVDYSNEIAAKYYESIITVVHST 907

  Fly   844 RQVKSRNEISKRH----HPQLSLFAQNTDSEGVLRRHLPQIKVLSRCEDVELELFDESSKISKQL 904
            |.:.:.|.|....    ||........|.....::..:.:.|.||..::.    ||....:..::
pombe   908 RSMMAENGIKSDAVVYIHPDEEHSKLITSESASIQSLIKKCKTLSIVDNT----FDSDKCVKNEV 968

  Fly   905 SYFST 909
            ...||
pombe   969 LEGST 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ValRS-m	NP_648268.1	PTZ00419	23..989	CDD:240411	353/915 (39%)
vrs1	NP_595435.1	PTZ00419	82..977	CDD:240411	353/915 (39%)