Protein Alignment ValRS-m and ValRS

DIOPT Version :10

• Sequence 1: NP_648268.1
• Gene: ValRS-m / 39023
• FlyBaseID: FBgn0035942
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_061513040.1
• Gene: ValRS / 1272628
• VectorBaseID: AGAMI1_008405
• Length: 1046
• Species: Anopheles gambiae
• Alignment Length: 1022
• Identity: 377/1022 - (36%)
• Similarity: 555/1022 - (54%)
• Gaps: 117/1022 - (11%)

  Fly    15 KYLCQPRVYSLYYSTLKDAANE---LPLAAGYQPQPVENA---YWERE--------HRQANLPKA 65
            |.:.:.:|.::|..:.|:...:   .|....|.||.||.|   :||:|        .|:.|.||
Mosquito    58 KKVKETKVVAVYSGSTKEGEKKDLSGPFPDAYSPQYVEAAWYSWWEKEGFFKPEYGQRKLNNPK- 121

  Fly    66 SASSCKRGTYRMLLPPPNVTGNLHLGHALMATVQDVIARQREQLGYQVDWVPGTDHAGIATQVVV 130
                   |.:.|::|||||||:|||||||...::|.|.|.....|....||||.|||||||||||
Mosquito   122 -------GQFVMVIPPPNVTGSLHLGHALTNAIEDAITRWHRMKGRTTLWVPGCDHAGIATQVVV 179

  Fly   131 ERTIAASQAKTRHELGRSAFLDEVWRWKAEKGAGIVQDLRQLGCKLNWQREYFTMDEQQAHAVNV 195
            |:.:.....:|||:|||..|:|::|:|:.|||..|...|::||...:|.|..||||.:...||..
Mosquito   180 EKKLWREHKQTRHDLGREKFIDKIWQWRNEKGDRIYHQLKKLGSSFDWDRACFTMDPKLCKAVTE 244

  Fly   196 AFERLFEEGLIQRRNSVVNWCTALRSAISDIEVDSVEITEPVEISVPGYDHKVLFGRMYDFAYHV 260
            ||.|:.|.|:|.|.:.:|||...|||||||||||.||::...::|:|||..||.||.:..|||.|
Mosquito   245 AFVRMHEMGMIYRSSRLVNWSCTLRSAISDIEVDKVEVSGRTQLSIPGYADKVEFGVLVSFAYKV 309

  Fly   261 VDGEALPDGSVEEIVVSTTRPETILGDVAVAVHPLDPRYAKYRNIDQVKLKHPFRDDTIPLVFDI 325
            :..|:      :||||:|||.||:|||.||||||.|.|   |:::....::|||.|..:|:|.|.
Mosquito   310 IGSES------DEIVVATTRVETMLGDTAVAVHPKDTR---YQHLHGKFVQHPFCDRKLPIVCDE 365

  Fly   326 TVDQEFGTGAVKITPAHDKFDFELATRHKLEPRQVFTETGLVVDAYSEYKGIPRFEARDLIVNRL 390
            .|:..|||||||||||||..|:::..||.|....:|::.|::|..|..:.|:.||:||..|:..|
Mosquito   366 FVEMAFGTGAVKITPAHDPNDYDVGKRHNLPFITIFSDDGIIVGDYGSFTGMKRFDARKAILVAL 430

  Fly   391 EEMDLLRQVRSHTMQLPICSRSKDVIEYMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETEW 455
            :|..|.|..:.:.|.:|:||||||::|.:|.|||::||.::|.:|...:.:|.|.|.|...:..|
Mosquito   431 QEKGLYRDTKDNPMVVPVCSRSKDIVEPLIKPQWYVKCSEMAANATEAVRTGALAITPDVHKKIW 495

  Fly   456 ERWLQDSRDWCISRQLWWGHQVPAYEVI---------DSQGNSQWVAALDEKTARQKAMRLIGSE 511
            ..|:.:.||||:||||||||::|||:|:         :....:.|.....|..|..||...:..:
Mosquito   496 YHWMDEIRDWCVSRQLWWGHRIPAYQVVFKDPAKAPKNLSDENLWFVGRTEAEALSKAASTLKVD 560

  Fly   512 E--FTLKRDPDVLDTWFSSSLLPFSTAGWPE--ESYKERYPLDIMQTGHDIIFFWVARMMMLGLK 572
            :  .::|:|.|||||||||.|.|||..|||:  :..|..||..:::|||||:|||||||:..|..
Mosquito   561 KALISMKQDEDVLDTWFSSGLFPFSVFGWPDNTDDLKLFYPTTLLETGHDILFFWVARMVFFGQT 625

  Fly   573 LTGEAPFQRILLNGIVCDAHGRKMSKSIGNIVAPQQVVQGASLESLKAGLEQSCEAGIITPSELK 637
            |.|:.||:.:.|:.:|.||||||||||:||::.|..|:.|.|||    ||.:......:.|.|::
Mosquito   626 LLGKLPFKEVFLHPMVRDAHGRKMSKSLGNVIDPMDVITGISLE----GLHKQLYDSNLDPREIE 686

  Fly   638 ASTIGMTQMFPNGIQECGTDALRFTLMSHNIKSHFISFDVNACHTNKLFLNKVWQAMRFTL---- 698
            .:..|..|.:||||.|||||||||.|.::..::..|:.|:......:.|.||:|.|.:|.|
Mosquito   687 KAKAGQKQDYPNGIPECGTDALRFALCAYMTQARDINLDIQRVQGYRFFCNKLWNATKFALMYFP 751

  Fly   699 GSAKGLGISLHQFETLEGVNLGLWDRWIVGRLAETLSVCSQSYSNYNFHLATAALKTFFYQYLCD 763
            |:.|     .....:|:|:...| ||||:.|||..:...::.:..|.|.|||.|...|:...|||
Mosquito   752 GAEK-----YDIITSLDGLESNL-DRWILSRLAGCIETANRGFEKYEFALATNACYNFWLYDLCD 810

  Fly   764 TYLETTKPAI--GNRSADAYIHVGTLTACLSWGLQAMAPYAPFVASELLQHVPLN---------- 816
            .|||..|...  .:.||.|... .||..||:.||:.::|:.||:..||.|.:|..
Mosquito   811 VYLECLKSVFQTNDESAKASAR-RTLYTCLNLGLKLLSPFMPFITEELYQRLPRGDFATVASICV 874

  Fly   817 ---IELKLSDYKDEKLEEEVNEIVNICHNVRQVKSRNEISKRHHPQLSLFAQNTDSEGVLRRHLP 878
               .|...|.:|||.:|:....:.....::|..:|...|..:..........:......|.|...
Mosquito   875 ASYPEQTDSPWKDESIEKGFEFVQKTARDIRSARSDYNIPNKTKTDAYFICSDEGVRSALERFTL 939

  Fly   879 QIKVLS---------------------RC-----------EDVELELFDESSKISKQ-LSYFSTA 910
            :::.::                     :|           .|.|:|...:..:..:| ::....|
Mosquito   940 ELETMAFSQVHFGTVPPAGCAILTISGQCVVHLMLKGLIEVDKEIEKMTKKQEALQQTIAKLQQA 1004

  Fly   911 GALCSFGLKLSDGLDLTPEKRDEMQKANAKKLKKLVTELQRYRMRLD 957
            .|:.::..|:       ||   :::|||.:||.:...|::|....:|
Mosquito  1005 MAVPNYANKV-------PE---DVRKANVEKLDQSKVEIERLSSAID 1041

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ValRS-m	NP_648268.1	PTZ00419	23..989	CDD:240411	375/1014 (37%)
ValRS	XP_061513040.1	None