Protein Alignment ValRS-m and vars2

DIOPT Version :10

• Sequence 1: NP_648268.1
• Gene: ValRS-m / 39023
• FlyBaseID: FBgn0035942
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_002940996.3
• Gene: vars2 / 100493727
• XenbaseID: XB-GENE-6046089
• Length: 1033
• Species: Xenopus tropicalis
• Alignment Length: 1009
• Identity: 396/1009 - (39%)
• Similarity: 569/1009 - (56%)
• Gaps: 99/1009 - (9%)

  Fly    31 KDAANELPLAAGYQPQPVENA---YWERE-----HRQANLPKASASSCKRGTYRMLLPPPNVTGN 87
            ||.:  :||...|.|:.||.|   :|.|:     ..|:..|...:.     ||.:.:|||||||:
 Frog    74 KDIS--VPLPHSYSPRYVEAAWYPWWVRQGFFKPEYQSQQPHNGSE-----TYSLCIPPPNVTGS 131

  Fly    88 LHLGHALMATVQDVIARQREQLGYQVDWVPGTDHAGIATQVVVERTIAASQAKTRHELGRSAFLD 152
            ||:||||...::|.:.|.:..||::|.||||:||||||||.|||:.:...:...||:..|..||.
 Frog   132 LHIGHALTVAIEDSLVRWKRMLGHKVLWVPGSDHAGIATQAVVEKKLLKEKGLLRHDFSREEFLK 196

  Fly   153 EVWRWKAEKGAGIVQDLRQLGCKLNWQREYFTMDEQQAHAVNVAFERLFEEGLIQRRNSVVNWCT 217
            |||:||.|||..|...||.||..|:|.|..||||:..:.||:.||.||..:||:.|...:|||..
 Frog   197 EVWKWKEEKGDIIYHQLRSLGASLDWDRCCFTMDKMFSRAVSEAFVRLHNDGLVYRHLRLVNWSC 261

  Fly   218 ALRSAISDIEVDSVEITEPVEISVPGYDHKVLFGRMYDFAYHVVDGEALPDGSVEEIVVSTTRPE 282
            |||||||||||||.::|....||||||:.|:.||.::.|||       :.:|..:||:|||||||
 Frog   262 ALRSAISDIEVDSRQLTGKTYISVPGYERKIPFGLLFSFAY-------VTEGGDDEIIVSTTRPE 319

  Fly   283 TILGDVAVAVHPLDPRYAKYRNIDQVKLKHPFRDDTIPLVFDITVDQEFGTGAVKITPAHDKFDF 347
            |:|||.||||||.||||.::..   .:|.|||....||:|....|:.:|||||||:||||...||
 Frog   320 TMLGDTAVAVHPNDPRYLRFHG---TRLHHPFTGQLIPVVTHDFVNPDFGTGAVKVTPAHSLADF 381

  Fly   348 ELATRHKLEPRQVFTETGLVVDAYSEY-KGIPRFEARDLIVNRLEEMDLLRQVRSHTMQLPICSR 411
            |:|....|....|..|.||:.:...|: :|:.||:||:.|::.|:|..|.|....|.|.||:|||
 Frog   382 EMAQSLDLPVVSVIGEDGLMTENSGEWIQGVKRFDAREQILSALKEKGLYRGDYEHAMVLPVCSR 446

  Fly   412 SKDVIEYMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETEWERWLQDSRDWCISRQLWWGHQ 476
            |.||||.::..|||:.||.:|:.||..::.|:|:|:|...:..|..||.:..|||:|||||||||
 Frog   447 SGDVIEQLLKRQWFVSCKKMAQKALEAVNVGQLKIIPSFHQKNWNHWLSNISDWCVSRQLWWGHQ 511

  Fly   477 VPAYEVIDSQGNSQ----------WVAALDEKTARQKAMRLI--GSEEFTLKRDPDVLDTWFSSS 529
            :|||.|..|:..|.          ||.|.:|..|::||.:.:  ..::.::|||.|||||||||:
 Frog   512 IPAYHVAVSEAQSDKDIRDEQEEIWVVAHNESEAKKKASKKLRRPEKDLSVKRDEDVLDTWFSSA 576

  Fly   530 LLPFSTAGWPEES--YKERYPLDIMQTGHDIIFFWVARMMMLGLKLTGEAPFQRILLNGIVCDAH 592
            |.||:..||||.:  .|:.||..:::||.|::|||||||:|||..|||:.||:.:.|:.:|.|||
 Frog   577 LFPFAMLGWPENTSDLKDFYPNSLLETGSDLLFFWVARMVMLGEHLTGKLPFKEVFLHSMVRDAH 641

  Fly   593 GRKMSKSIGNIVAPQQVVQGASLESLKAGLEQSCEAGIITPSELKASTIGMTQMFPNGIQECGTD 657
            |||||||:||::.|..|:.|.|||.|:..|:.    |.:.|.|||.:..|:.:.||.||.|||||
 Frog   642 GRKMSKSLGNVIDPLDVITGISLEELQNRLQD----GNLDPRELKVAEAGLLKAFPRGIPECGTD 702

  Fly   658 ALRFTLMSHNIKSHFISFDVNACHTNKLFLNKVWQAMRFTLGSAKGLGISLHQFETLEGVNLGLW 722
            ||||.|.|:.::...|:.||.:....:.|.||:|..::|||.|   ||.|.......|....|..
 Frog   703 ALRFALCSYKVQGDDINLDVPSVLAVRHFCNKIWNGIKFTLSS---LGESFSPIPVEEFKPQGPM 764

  Fly   723 DRWIVGRLAETLSVCSQSYSNYNFHLATAALKTFFYQYLCDTYLETTKPAI-GNRSADAYIHVGT 786
            |||::..|......|.:.:..|..|.||.|::||:.|..||.|:|..||.: |...:||
 Frog   765 DRWLLDHLRLLTEECERRFQAYELHGATGAIQTFWVQSYCDFYVEAVKPILKGPHGSDA------ 823

  Fly   787 LTACLSWG----LQAMAPYAPFVASELLQHVP---LNIELKL--------SDYKDEKLEEEVNE- 835
             ...|.||    |:.:||:.||:..||.|..|   :|....:        |.....:..|||.:
 Frog   824 -QQTLYWGAEIVLRLLAPFTPFLCEELWQRFPSASVNCAPSICVAQYPTPSQMAHWRYPEEVQQF 887

  Fly   836 --IVNICHNVRQVKSRNEISKRHHPQLSLFAQNTDSEGVLR---RHLPQIKVLSRCEDVELELFD 895
              :.::...||.::|...::|. .|::.:|....:....|:   .|||   .||....:::.:..
 Frog   888 DFVQSVIRTVRSLRSDYHMTKA-RPEVHIFCSMEEHLNALQSFHSHLP---TLSHSGPIQVHMLQ 948

  Fly   896 ESSKISKQLSYFST--AGALCSFGLKLSDGLDLTPEKRDEMQKANAK--KLKKLVTELQRYRMRL 956
            ::|:..:....::|  ....|...:||...||    ...|:.|.:.|  .|:.....:.:|. ..
 Frog   949 DASQFREDPVGWATEKVSEGCYLRVKLQGLLD----PHTELAKLHKKHQNLQLQFINMSKYE-NG 1008

  Fly   957 DNEAFQLMADKKVKSHFENKVKELEAEINSLTRL 990
            |||      ||.:    :.|:.:::..:.:|.|:
 Frog  1009 DNE------DKSI----QQKISKVQCTMETLQRM 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ValRS-m	NP_648268.1	PTZ00419	23..989	CDD:240411	395/1006 (39%)
vars2	XP_002940996.3	PTZ00419	57..1033	CDD:240411	396/1009 (39%)