Protein Alignment ValRS-m and vars1

DIOPT Version :10

• Sequence 1: NP_648268.1
• Gene: ValRS-m / 39023
• FlyBaseID: FBgn0035942
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_002939512.3
• Gene: vars1 / 100489760
• XenbaseID: XB-GENE-487344
• Length: 1243
• Species: Xenopus tropicalis
• Alignment Length: 1003
• Identity: 394/1003 - (39%)
• Similarity: 576/1003 - (57%)
• Gaps: 79/1003 - (7%)

  Fly    31 KDAANELPLAAGYQPQPVENA---YWEREHRQANLPKASASSCK----RGTYRMLLPPPNVTGNL 88
            ||.:.  |:...|.||.||:|   :||:|  :...|:...||..    :|.:.|.:|||||||:|
 Frog   271 KDVSG--PMPDSYSPQYVESAWYSWWEKE--KFFKPEFGRSSISEPNPKGLFMMCIPPPNVTGSL 331

  Fly    89 HLGHALMATVQDVIARQREQLGYQVDWVPGTDHAGIATQVVVERTIAASQAKTRHELGRSAFLDE 153
            ||||||...:||.:.|.....|....|.||.||||||||||||:.:...:.||||:.||..|::|
 Frog   332 HLGHALTNAIQDCLTRWHRMRGELTLWNPGCDHAGIATQVVVEKKLWRERGKTRHDFGRENFIEE 396

  Fly   154 VWRWKAEKGAGIVQDLRQLGCKLNWQREYFTMDEQQAHAVNVAFERLFEEGLIQRRNSVVNWCTA 218
            ||:||.|||..|...||.||..|:|.|..||||.:.:.||..||.||.|.|:|.|...:|||...
 Frog   397 VWKWKREKGDRIYHQLRILGSSLDWDRTCFTMDPKLSFAVQEAFIRLHEAGIIYRSKRLVNWSCT 461

  Fly   219 LRSAISDIEVDSVEITEPVEISVPGYDHKVLFGRMYDFAYHVVDGEALPDGSVEEIVVSTTRPET 283
            |.|||||||||..|::....:.||||...|.||.:..|||.|.:       :.|||||:|||.||
 Frog   462 LNSAISDIEVDKKELSGRTLLPVPGYKQGVEFGVLVSFAYKVQE-------TGEEIVVATTRVET 519

  Fly   284 ILGDVAVAVHPLDPRYAKYRNIDQVKLKHPFRDDTIPLVFDITVDQEFGTGAVKITPAHDKFDFE 348
            :|||.||||||.|.|   |:::....:.|||....:|:|||..||..|||||||||||||..|:|
 Frog   520 MLGDTAVAVHPQDQR---YKHLKGHHVLHPFCSRLLPIVFDEFVDMSFGTGAVKITPAHDPTDYE 581

  Fly   349 LATRHKLEPRQVFTETGLVVDAYSEYKGIPRFEARDLIVNRLEEMDLLRQVRSHTMQLPICSRSK 413
            :..||.|:...:..:.|.:::....:.|:.||:||..:::.|:|..|.::|:.:.|.:|:|||||
 Frog   582 VGMRHSLDFVNIMDDNGTLINVPQPFLGMKRFDARKAVLDALKEKGLFKEVKDNPMVVPVCSRSK 646

  Fly   414 DVIEYMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETE-WERWLQDSRDWCISRQLWWGHQV 477
            |::|.::.|||:::|.::.|.|...:..|.| ::.|.|.|: |..|:.:.|||||||||||||::
 Frog   647 DIVEPLLKPQWYVRCDEMGKRAADAVRDGHL-LIKPEFHTKTWFIWMDNIRDWCISRQLWWGHRI 710

  Fly   478 PAYEVI----------DSQGNSQWVAALDEKTARQKAMRL--IGSEEFTLKRDPDVLDTWFSSSL 530
            |||.|.          |:.| ..|::...|:.|::||.|:  :..|:.:|::|.|||||||||.:
 Frog   711 PAYFVTVNDPSVPAGEDTDG-KYWISGRSEQEAKEKAARVFNVAPEKISLRQDDDVLDTWFSSGI 774

  Fly   531 LPFSTAGWPE--ESYKERYPLDIMQTGHDIIFFWVARMMMLGLKLTGEAPFQRILLNGIVCDAHG 593
            .|||..|||.  |.....||..:::|||||:|||||||:||||.|||:.||:.:.|:.:|.||||
 Frog   775 FPFSIFGWPNQTEDLNVFYPGTLLETGHDILFFWVARMVMLGLTLTGKLPFKEVYLHAVVRDAHG 839

  Fly   594 RKMSKSIGNIVAPQQVVQGASLESLKAGLEQSCEAGIITPSELKASTIGMTQMFPNGIQECGTDA 658
            ||||||:||::.|..|:.|.:||.|...|.:|    .:.|:||:.:..|....:||||.||||||
 Frog   840 RKMSKSLGNVIDPLDVINGITLEGLNKQLLES----NLDPAELERAKDGQKSDYPNGIPECGTDA 900

  Fly   659 LRFTLMSHNIKSHFISFDVNACHTNKLFLNKVWQAMRFTLGSAKGLG--ISLHQFETLEGVNLGL 721
            |||.|.::..:...|:.|||.....:.|.||:|.|.:|.:   ||||  .|...|....|.. .|
 Frog   901 LRFALCAYTSQGRDINLDVNRILGYRHFCNKIWNATKFAM---KGLGDNYSPPDFAGACGQE-SL 961

  Fly   722 WDRWIVGRLAETLSVCSQSYSNYNFHLATAALKTFFYQYLCDTYLETTKPAIGNRSADAYIHVG- 785
            .||||:.||:..:.:|:..:.||:|...|.|:..|:...|||.|||..||...: |.:|.|.||
 Frog   962 ADRWILSRLSFAVDLCNNGFQNYDFPGITTAVYNFWLYELCDVYLECLKPVFLS-SDEAAISVGR 1025

  Fly   786 -TLTACLSWGLQAMAPYAPFVASELLQHVP---------LNI----ELKLSDYKDEKLEEEVNEI 836
             ||..||..||:.::|:.||:..||.|.:|         :::    |....:::||::|..::..
 Frog  1026 NTLYTCLDAGLRLLSPFMPFLTEELYQRLPRRSSSRTPSISVTSYPETSECNWRDEEIERNMDLA 1090

  Fly   837 VNICHNVRQVKSRNEISKRHHPQLSLF--AQNTDSEGVLRRHLPQIKVLSRCED-VELELFDESS 898
            :.|..::|.:::...::|   .:...|  .|:.|:..|:..:...|.|||.... |.|:..|.:.
 Frog  1091 LLIVKSIRSLRADYNLTK---TKADCFVQCQDADTVSVVTAYTSFITVLSSSRSLVTLKAQDPAP 1152

  Fly   899 KISKQLSYFSTAGALCSFGLKLSDGLDLTPEKRDEMQKANAKKLKKLVTELQRYRMRLDNEAFQL 963
            ..|.    .:||....:..:.|...:|:  ||  |:.|...|| .:|..:|::.|.|:.:..::.
 Frog  1153 AGSA----VNTASDKATVYVVLKGLIDV--EK--ELAKLQVKK-TELGRQLEKLRERMGSADYRS 1208

  Fly   964 MADKKVKSHFENKVKELEAEINSLTRLA 991
            ...:.|:.....::::.|.|...:...|
 Frog  1209 KVPETVQQQDAERIRQTETEFKKVNEAA 1236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ValRS-m	NP_648268.1	PTZ00419	23..989	CDD:240411	393/999 (39%)
vars1	XP_002939512.3	GST_C_family	79..192	CDD:470672
		PTZ00419	263..1242	CDD:240411	394/1003 (39%)