Protein Alignment orb2 and CPEB1

DIOPT Version :9

• Sequence 1: NP_001356977.1
• Gene: orb2 / 39018
• FlyBaseID: FBgn0264307
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: NP_001373990.1
• Gene: CPEB1 / 64506
• HGNCID: 21744
• Length: 593
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 132/403 - (32%)
• Similarity: 189/403 - (46%)
• Gaps: 101/403 - (25%)

  Fly   366 NGGGDGSNSMSLMQDRMRVM----------GGPKHLSEADAMAIAASGNDPSVYLNALKMGSPSR 420
            :|...||:.:|.:...:|:.          |||:               ||      ||||..||
Human   216 SGFSSGSDHLSDLISSLRISPPLPFLSLSGGGPR---------------DP------LKMGVGSR 259

  Fly   421 LSPH---------SPHSPIQGGNGGN-----------------------------VGDGTAR--- 444
            :...         ||.|..:...|.:                             |.:.|..
Human   260 MDQEQAALAAVTPSPTSASKRWPGASVWPSWDLLEAPKDPFSIEREARLHRQAAAVNEATCTWSG 324

  Fly   445 -----------FSRKVFVGGLPPDIDEDEITTSFRRFGPLVVDWPHKAESKSYFP-----PKGYA 493
                       :|.|||:||:|.||.|..:..:||.||.|.|:||.|.......|     ||||.
Human   325 QLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYV 389

  Fly   494 FLLFQDESSVQQLIDSCITDE------DKLYLCVSSPTIKDKAVQIRPWRLADADYVLDATMSLD 552
            :|:|:.|.||:.|:.:|..|.      .:.|..:||..::.|.||:.||.|||:::|...:..||
Human   390 YLVFELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLD 454

  Fly   553 PRKTVFVGGVPRPLKAFELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISAR 617
            |.:|||||.:...|.|..||.|::.|:|||.|||||||.. |||.|:|||.|:||:||:.|:||.
Human   455 PSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKAVSAA 518

  Fly   618 FVQLQHGDIDKRVEVKPYVLDDQMCDECEGQRCGGKFAPFFCANVTCLQYYCEHCWAVIHSRPGR 682
            ||:::.....|:|::.|| |:|.:|..|..|.     .||||.:..|.:|:|..||...||..|.
Human   519 FVEIKTTKFTKKVQIDPY-LEDSLCHICSSQP-----GPFFCRDQVCFKYFCRSCWHWRHSMEGL 577

  Fly   683 EYHKPLVKEGADR 695
            .:|.||::...:|
Human   578 RHHSPLMRNQKNR 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
orb2	NP_001356977.1	RRM1_CPEB2_like	447..538	CDD:241168	39/101 (39%)
		RRM2_CPEB2_like	555..635	CDD:241170	40/79 (51%)
		CEBP_ZZ	630..691	CDD:318563	23/60 (38%)
CPEB1	NP_001373990.1	CEBP1_N	31..334	CDD:406706	22/138 (16%)
		RRM1_CPEB1	336..443	CDD:410122	42/106 (40%)
		RRM2_CPEB1	454..537	CDD:410124	44/84 (52%)
		CEBP_ZZ	531..586	CDD:406704	23/60 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0129
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810