Protein Alignment Tsp66E and Cd82

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_113985.2
• Gene: Cd82 / 83628
• RGDID: 69070
• Length: 266
• Species: Rattus norvegicus
• Alignment Length: 267
• Identity: 81/267 - (30%)
• Similarity: 133/267 - (49%)
• Gaps: 30/267 - (11%)

  Fly     6 GVWC---AKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLA 67
            |..|   .||.|.:||.:||:||.:|.|.|:|:..||.|.|::|:          |...:::..|
  Rat     2 GAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILADKSSFISVLQ----------TSSSSLQVGA 56

  Fly    68 YVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFL 132
            ||.:.:||:...|.|||.:||:.|.||||..|..||:|:|||::..|.|..|..||::.|..|.:
  Rat    57 YVFIGVGAITMLMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKQEMGNTV 121

  Fly   133 QTTITSYSLGENVDATSL---MWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKD 194
            ...|.:||    |:|:|.   .|:.:.....|||.....::..:|...|.. ..|.|.:|...|:
  Rat   122 MDIIQNYS----VNASSSREEAWDYVQAQVKCCGWVSPSNWTRNPVLKNST-KTTYPCSCEKTKE 181

  Fly   195 V-AKLVPRDEDCTTNPSDSNS-------FYKKGCYEVFTEWLIRQRELVI-VAIAVGIVHLVLII 250
            . .:|:.:...|.::.|.::.       .:.:||.|....||.....::: |...|.::.|:.:.
  Rat   182 EDNQLIVKKGFCESDNSTASENSPEDWPVHPEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLF 246

  Fly   251 LAFALCK 257
            |:..||:
  Rat   247 LSICLCR 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	78/257 (30%)
		tetraspanin_LEL	120..228	CDD:351888	26/118 (22%)
Cd82	NP_113985.2	Tetraspanin	24..253	CDD:459767	70/243 (29%)
		CD37_CD82_like_LEL	106..228	CDD:239413	29/126 (23%)