Protein Alignment Tsp66E and TSPAN4

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001426622.1
• Gene: TSPAN4 / 7106
• HGNCID: 11859
• Length: 330
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 74/262 - (28%)
• Similarity: 118/262 - (45%)
• Gaps: 49/262 - (18%)

  Fly     5 CG-----VWCAKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIE 64
            ||     :...|||:..||.:|::.|..:.|||:|||..:.|...|        ...|....|
Human    91 CGMARACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATL--------SSSFPSLSA-- 145

  Fly    65 QLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESK 129
              |.:|::.||.:..:.|:|.|||::|::|||.|:...|:|:.:.|.....|...:.||:...::
Human   146 --ANLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQ 208

  Fly   130 NFLQTTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKD 194
            ..|:..:..|....||..|: .|:.:..:|.|||:::|.|      |........:||:||:
Human   209 QDLKKGLHLYGTQGNVGLTN-AWSIIQTDFRCCGVSNYTD------WFEVYNATRVPDSCCL--- 263

  Fly   195 VAKLVPRDEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGIVHLVLIILAFALCKAF 259
                 ...|.|..:.  ..:::|..|||....||  |..|    :||||         |.||.|.
Human   264 -----EFSESCGLHA--PGTWWKAPCYETVKVWL--QENL----LAVGI---------FGLCTAL 306

  Fly   260 AK 261
            .:
Human   307 VQ 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	70/245 (29%)
		tetraspanin_LEL	120..228	CDD:351888	25/107 (23%)
TSPAN4	NP_001426622.1	None