Protein Alignment Tsp66E and Tspan15

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_932113.2
• Gene: Tspan15 / 70423
• MGIID: 1917673
• Length: 294
• Species: Mus musculus
• Alignment Length: 269
• Identity: 64/269 - (23%)
• Similarity: 115/269 - (42%)
• Gaps: 69/269 - (25%)

  Fly     8 WCA-------KYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQ 65
            :||       |:.|.|::.:|:::|.::..||::              .|:||.:..|...|...
Mouse    11 YCARFSYLWLKFSLIIYSTVFWLIGGLVLSVGIY--------------AEAERQKYKTLESAFLA 61

  Fly    66 LAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGA---------FFK 121
            .|.:|:::|.|||.:||:|.|.::|::.|||.::...|.:.|:.|:: ||:.|         |..
Mouse    62 PAIILILLGVVMFIVSFIGVLASLRDNLCLLQSFMYILGICLVMELI-GGIVALIFRNQTIDFLN 125

  Fly   122 DKVRAESKNFLQTTITSYSLGENVDATSLMWNQLMGNFGCCG--------INDYHDFDASPAWVN 178
            |.:|...:|:.          :::|..::| :.:...|.|||        .|.|||..|......
Mouse   126 DNIRRGIENYY----------DDLDFKNIM-DFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLAC 179

  Fly   179 GKGNRTIPDACCI--LKDVAKLVPRDEDCTTNPSD------SNSFYKKGCYEVFTEWLIRQRELV 235
            |     :|..|||  ..||...:     |.....|      .|..:.:||......|.: ....:
Mouse   180 G-----VPYTCCIRNTTDVVNTM-----CGYKTIDKERLNAQNIIHVRGCTNAVLIWFM-DNYTI 233

  Fly   236 IVAIAVGIV 244
            :..:.:||:
Mouse   234 MAGLLLGIL 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	62/259 (24%)
		tetraspanin_LEL	120..228	CDD:351888	26/123 (21%)
Tspan15	NP_932113.2	Tetraspanin	20..>157	CDD:459767	41/162 (25%)
		penumbra_like_LEL	114..231	CDD:239411	28/138 (20%)