Protein Alignment Tsp66E and Tspan1

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_598442.1
• Gene: Tspan1 / 66805
• MGIID: 1914055
• Length: 240
• Species: Mus musculus
• Alignment Length: 247
• Identity: 74/247 - (29%)
• Similarity: 117/247 - (47%)
• Gaps: 23/247 - (9%)

  Fly    11 KYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVIGA 75
            |.::.:||.:.|:.|..:..||:|::||..|.:.:...:.|..: ||.      .:.|.|:..||
Mouse     8 KVMMFLFNLLIFLCGAALLAVGIWVSVDGTSFLKVFGSLSSSAM-QFV------NVGYFLIAAGA 65

  Fly    76 VMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSYS 140
            |:|.:.|||..||..|::|:|..:.:.|:::.|||| ||.:.|.....:..:....|........
Mouse    66 VLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEI-AGAVVALVYTTLAEQFLTLLVVPAIEKD 129

  Fly   141 LGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAKLVPRDEDC 205
            .|...|.|. :||..|....|||.|:|.||:|| .:|  |.|:..|..||.......:.|    |
Mouse   130 YGYQTDFTQ-VWNTTMEELHCCGFNNYTDFNAS-RFV--KENKVFPPPCCANPGNHTVEP----C 186

  Fly   206 TTNPSDSNSFYKKGCYEVFTEWL--IRQRELVIVAIAVGIVHLVLIILAFAL 255
            |  ...:.|...:||   |.|.|  ||...:.:..:|||:..|.|..:..::
Mouse   187 T--EEKAKSMKVQGC---FKEILHRIRANAVTVGGVAVGVAALELAAMVVSM 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	74/247 (30%)
		tetraspanin_LEL	120..228	CDD:351888	30/107 (28%)
Tspan1	NP_598442.1	Tetraspanin	7..>151	CDD:459767	44/151 (29%)
		uroplakin_I_like_LEL	106..208	CDD:239409	32/114 (28%)