Protein Alignment Tsp66E and prph2a

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_571641.1
• Gene: prph2a / 58085
• ZFINID: ZDB-GENE-000616-8
• Length: 345
• Species: Danio rerio
• Alignment Length: 320
• Identity: 50/320 - (15%)
• Similarity: 101/320 - (31%)
• Gaps: 138/320 - (43%)

  Fly    13 LLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVIGAVM 77
            :|.:..:...:.|.::|.:||:..::......|:...||..:..            :|:.:|.:
Zfish    19 MLWLMYWFSVMAGVLVFSMGLFFKIELRKRSELMDNNESHFVPN------------ILIGVGLL- 70

  Fly    78 FFMSFLGYLGAMRESRCLLSTYG---------------------TFLILLLI------------- 108
                           .|.|:.:|                     .|||..|:
Zfish    71 ---------------ACCLNAFGGKVCYDSLDSSKYAKWKSIMTPFLICCLVFNFLLIVTAAMCF 120

  Fly   109 ----------AEIVAGGLGAFFKDKVRAESKNFLQTTITSYSLGENVDATSLMWNQLMGNFGCCG 163
                      ||.:..|: .::|| .....:.:::.|:                :.:...|.|||
Zfish   121 AMRIPLEFTLAEGLKNGM-KYYKD-TDTPGRCYMKRTL----------------DLMQMEFRCCG 167

  Fly   164 INDYHDF-------------------DASPAWVNGK----GNRTIPDACCILKDVAKLVPRDEDC 205
            .|:|.|:                   |...:.|:||    |   :|.:||   :.:...|..:..
Zfish   168 NNNYKDWFEIQWVSNRYLDFSAKEVKDRISSNVDGKYLMDG---VPFSCC---NPSSPRPCIQQQ 226

  Fly   206 TTNPSDSNSF---------YKKGCYEVFTEW----------LIRQRELVIVAIAVGIVHL 246
            .||.|...|:         :|:||.:....:          |:....|:..|:.:|:.::
Zfish   227 ITNNSAHYSYDHYTEDLNIWKRGCRDALVSYYGGMMNTIGVLVLLVTLLQSAVMIGLQYI 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	50/320 (16%)
		tetraspanin_LEL	120..228	CDD:351888	26/149 (17%)
prph2a	NP_571641.1	Tetraspanin	16..>167	CDD:459767	25/193 (13%)
		peripherin_like_LEL	120..262	CDD:239415	29/165 (18%)