Protein Alignment Tsp66E and tspan33b

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_005159085.1
• Gene: tspan33b / 567512
• ZFINID: ZDB-GENE-060503-607
• Length: 266
• Species: Danio rerio
• Alignment Length: 250
• Identity: 61/250 - (24%)
• Similarity: 110/250 - (44%)
• Gaps: 43/250 - (17%)

  Fly    11 KYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVIGA 75
            :|.|..|:|:|:|...:|..:|::....        |..::.|......|      |.:|:|:|.
Zfish    21 RYFLFFFSFLFWVFSLLIVAIGVYAKAQ--------KATDTVRDSFLIDP------AVILIVVGV 71

  Fly    76 VMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSYS 140
            ||||::|.|.:||:||:..||..:...|.|:.:.::....||.|:.::.|.....|::..|..|.
Zfish    72 VMFFITFCGCIGALRENIRLLKIFSFSLTLVFLTQMAIAILGFFYSEQTRDALGEFVKKAIVHYR 136

  Fly   141 LGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNR-----TIPDACCILKDVAKLVP 200
              :::|..:|| :.:...|.|||..:|.|:..:|.:.....|.     ::|.:||        .|
Zfish   137 --DDLDLQNLM-DYIQKEFKCCGWTNYTDWSWNPYFNCSSSNPSNERCSVPFSCC--------TP 190

  Fly   201 RDEDCTTNP------------SDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGI 243
            ...:...|.            :.:.|.|..||.:....| |....|:..|:.:|:
Zfish   191 LPRETVINSMCGFGIQTQNHLNATKSIYSVGCADRAVIW-IESHLLLFGALTLGL 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	61/249 (24%)
		tetraspanin_LEL	120..228	CDD:351888	24/124 (19%)
tspan33b	XP_005159085.1	Tetraspanin	36..>156	CDD:459767	35/136 (26%)
		penumbra_like_LEL	114..234	CDD:239411	27/131 (21%)