Protein Alignment Tsp66E and Tspan6

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_062630.2
• Gene: Tspan6 / 56496
• MGIID: 1926264
• Length: 245
• Species: Mus musculus
• Alignment Length: 256
• Identity: 67/256 - (26%)
• Similarity: 114/256 - (44%)
• Gaps: 37/256 - (14%)

  Fly     7 VWCAKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLL 71
            :.|.|.:|.|:.|||::.|.|:..||:|..|...:..:||.       |:.|      .:.:||:
Mouse    14 ITCLKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLN-------EKAT------NVPFVLI 65

  Fly    72 VIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTI 136
            ..|.|:..:...|.....|.|..:|..|..||.|:.:.|:||..:|..|:.:::...|:..:..:
Mouse    66 GTGTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENAL 130

  Fly   137 TSY-SLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAKLVP 200
            ..| |.|   |..|...:::.....|||:.:|.|:..:    |.......|.:||.|
Mouse   131 KEYNSTG---DYRSEAVDKIQSTLHCCGVTNYGDWKGT----NYYSETGFPKSCCKL-------- 180

  Fly   201 RDEDCTTNPSDSNSFYKKGCY-EVFTEWLIRQRELVIVAIAVGIV--HLVLIILAFALCKA 258
              |.|... .|::...::||: :|.|  .|.....|:..|:.|:.  .|:.|.||:.|.:|
Mouse   181 --EGCYPQ-RDADKVNEEGCFIKVMT--TIESEMGVVAGISFGVACFQLIGIFLAYCLSRA 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	65/249 (26%)
		tetraspanin_LEL	120..228	CDD:351888	24/109 (22%)
Tspan6	NP_062630.2	Tetraspanin	17..235	CDD:459767	65/250 (26%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	25/116 (22%)