Protein Alignment Tsp66E and Tspan5

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_006501799.1
• Gene: Tspan5 / 56224
• MGIID: 1928096
• Length: 311
• Species: Mus musculus
• Alignment Length: 276
• Identity: 79/276 - (28%)
• Similarity: 115/276 - (41%)
• Gaps: 51/276 - (18%)

  Fly     6 GVWCAKYLLCIFNFIFFV----LGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQL 66
            |.:|...:|....|:..:    ||....|:|||...:|..|         ..|...|.....:.:
Mouse    50 GCFCTVPVLRTAEFLVRIHSHFLGITFLGIGLWAWNEKGVL---------SNISSITDLGGFDPV 105

  Fly    67 AYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNF 131
             ::.||:|.|||.:.|.|.:||:||:..||..:..||.::...|:.||.|...|||.::.:...|
Mouse   106 -WLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFF 169

  Fly   132 LQTTITSY----SLGENVDATSLMWNQLMGNFGCCG--------INDYHDFDASPAWVNGKGNRT 184
            :...|.:|    .|...:|.|...|.       |||        :|.|.:...|    |....|.
Mouse   170 INNNIRAYRDDIDLQNLIDFTQEYWQ-------CCGAFGADDWNLNIYFNCTDS----NASRERC 223

  Fly   185 -IPDACCILKDVAKLVPRDE---DCTTNPSDSNS--FYKKGCYEVFTEWLIRQRELVIVA-IAVG 242
             :|.:|| .||.|:.|...:   |....|.....  .|.|||...|.:||  |..|.||| |.:|
Mouse   224 GVPFSCC-TKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWL--QDNLTIVAGIFIG 285

  Fly   243 IVHLVLIILAFALCKA 258
            |.    ::..|.:|.|
Mouse   286 IA----LLQIFGICLA 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	75/268 (28%)
		tetraspanin_LEL	120..228	CDD:351888	32/125 (26%)
Tspan5	XP_006501799.1	Tetraspanin	72..301	CDD:459767	75/254 (30%)
		TM4SF9_like_LEL	156..276	CDD:239412	35/133 (26%)