Protein Alignment Tsp66E and tspan4b

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001076276.1
• Gene: tspan4b / 556934
• ZFINID: ZDB-GENE-070410-127
• Length: 232
• Species: Danio rerio
• Alignment Length: 262
• Identity: 72/262 - (27%)
• Similarity: 126/262 - (48%)
• Gaps: 45/262 - (17%)

  Fly     9 CAKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQL--AYVLL 71
            |.|||:.:||.||::.|..:||||:|||..:....:|              |.:...|  |.:||
Zfish    10 CVKYLMFVFNLIFWLGGCGLFGVGVWLAFTQSEFSSL--------------PLSFPSLSAANLLL 60

  Fly    72 VIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTI 136
            |.|.|.....|||.|||::|.:|||.|:...|::|::.|:|...:.:.:.:::..::|:.|:..:
Zfish    61 VAGGVTMVTGFLGCLGALKEQKCLLLTFFVILLILVLTEVVLILVLSLYHEELDKKAKDDLREGM 125

  Fly   137 TSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAKLVPR 201
            ..||..   |.....|:.:...|.|||::::.|      |.|...:..:|.:||
Zfish   126 KGYSKN---DGLRKSWDNMQMIFKCCGVSNHTD------WHNKTTDGKLPGSCC----------- 170

  Fly   202 DEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELVI-VAIAVGIVHLVLIILAFAL-CKAF--AKY 262
                 :|...|...:::.|||...:||:.....|: ..:.:|||.|:.::.:..: |:..  .||
Zfish   171 -----SNDPSSCRHWEEPCYEKAKQWLLTNITSVLGFGVCIGIVQLLALVFSMLMYCQILRAEKY 230

  Fly   263 ND 264
            .|
Zfish   231 MD 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	67/249 (27%)
		tetraspanin_LEL	120..228	CDD:351888	21/107 (20%)
tspan4b	NP_001076276.1	Tetraspanin	11..222	CDD:459767	67/249 (27%)
		NET-5_like_LEL	108..196	CDD:239418	23/112 (21%)