Protein Alignment Tsp66E and tspan5b

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001008591.1
• Gene: tspan5b / 494048
• ZFINID: ZDB-GENE-041212-12
• Length: 271
• Species: Danio rerio
• Alignment Length: 271
• Identity: 79/271 - (29%)
• Similarity: 118/271 - (43%)
• Gaps: 51/271 - (18%)

  Fly     9 CAKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVI 73
            |.||.:..||.||::||.....|.||...:|..|         ..|...|.....:.: ::.||:
Zfish    14 CIKYFIFGFNIIFWLLGVAFLSVALWAWSEKGVL---------SNISSITDLGGFDPV-WLFLVV 68

  Fly    74 GAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITS 138
            |.|||.:.|.|.:||:||:..||..:..||.::...|:.||.|...|||.::.:.|.|:...|.:
Zfish    69 GGVMFVLGFAGCIGALRENSFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLKFFINNNIRA 133

  Fly   139 Y----SLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRT----------IPDAC 189
            |    .|...:|.|...|.       |||.....|::     :|...|.|          :|.:|
Zfish   134 YRDDIDLQNLIDFTQDYWE-------CCGAFGPEDWN-----LNIYFNCTDTNLSREKCGVPFSC 186

  Fly   190 CILKDVAKLVPRDEDC-----TTNPSDSNSF-YKKGCYEVFTEWLIRQRELVIVA-IAVGIVHLV 247
            | .||.|:.|...: |     .....:..:| :.|||...|.:||  |..|.:|| |.:||.
Zfish   187 C-TKDPAEDVINTQ-CGYDIRGKGDIEHKTFIHTKGCVPQFEKWL--QENLTVVAGIFIGIA--- 244

  Fly   248 LIILAFALCKA 258
             ::..|.:|.|
Zfish   245 -LLQIFGICLA 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	76/266 (29%)
		tetraspanin_LEL	120..228	CDD:351888	31/127 (24%)
tspan5b	NP_001008591.1	Tetraspanin	15..258	CDD:459767	78/270 (29%)
		TM4SF9_like_LEL	113..233	CDD:239412	34/135 (25%)