Protein Alignment Tsp66E and TSPAN11

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_011518981.1
• Gene: TSPAN11 / 441631
• HGNCID: 30795
• Length: 302
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 67/242 - (27%)
• Similarity: 107/242 - (44%)
• Gaps: 31/242 - (12%)

  Fly    11 KYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVIGA 75
            ||||.:|||.|:|.|..:..||:|..|:|...:::|            ........||:|:..|.
Human    17 KYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVL------------ASSTFAASAYILIFAGV 69

  Fly    76 VMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSYS 140
            ::....|||:...:.|.:..||||...|:::.:.|:|||.|...:..::..|.|..|..|
Human    70 LVMVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRT----- 129

  Fly   141 LGENV---DATSL--MWNQLMGNFGCCGINDYHDFDASP-AWVNGKGNRTIPDACCILKDVAKLV 199
            |.||.   .||.:  ..::|..:|.|||.|...|:..|. ..:.....|.:||:||     ..:|
Human   130 LAENYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCC-----KTVV 189

  Fly   200 PRDEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGIVHL 246
            .|   |......||.:..:|......|..:....|::.|:.:|:..|
Human   190 VR---CGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACL 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	67/242 (28%)
		tetraspanin_LEL	120..228	CDD:351888	29/113 (26%)
TSPAN11	XP_011518981.1	Tetraspanin	16..>158	CDD:459767	47/157 (30%)
		CD151_like_LEL	112..220	CDD:239408	29/120 (24%)