Protein Alignment Tsp66E and tspan33a

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001002617.2
• Gene: tspan33a / 436890
• ZFINID: ZDB-GENE-040718-361
• Length: 281
• Species: Danio rerio
• Alignment Length: 263
• Identity: 69/263 - (26%)
• Similarity: 126/263 - (47%)
• Gaps: 44/263 - (16%)

  Fly    11 KYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVIGA 75
            ||||..||.||:::..::..:|::..:.||........|:.               |.:|:|:|.
Zfish    22 KYLLFFFNMIFWIISLVLISIGVYSRIVKHETALACLTVDP---------------ALILMVVGI 71

  Fly    76 VMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSYS 140
            :|||::|.|.:|::||:.|||.|:..||.::.:.:::||.||..|.||.|.:..:.....|..|.
Zfish    72 LMFFITFCGCVGSLRENICLLQTFCIFLTIMFLLQLLAGVLGFVFSDKARGKVTDMFDNAIKHYR 136

  Fly   141 LGENVDATSLM-WNQLMGNFGCCGINDYHDF---------DASPAWVNGKGNRTIPDACCILKDV 195
              :::|..:|: :.|  ..|.|||...:.|:         |.:|:    :...::|.:||:....
Zfish   137 --DDLDLQNLIDYGQ--KQFNCCGGISFMDWSKNMYFNCSDDNPS----RERCSVPFSCCLHAKE 193

  Fly   196 AKLVPRDEDC-----TTNPSDSNSFYK-KGCYEVFTEWLIRQRELVIVAIAVG--IVHLVLIILA 252
            ..::  :..|     ..|...:::|.. .||.::...| |.....::..||:|  |..||.|:|:
Zfish   194 ETII--NTMCGHGMQALNYLAASAFINTNGCIDILVNW-IHSNLFLLGGIALGLTIPQLVGILLS 255

  Fly   253 FAL 255
            ..|
Zfish   256 QVL 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	69/263 (26%)
		tetraspanin_LEL	120..228	CDD:351888	24/123 (20%)
tspan33a	NP_001002617.2	Tetraspanin	21..260	CDD:459767	69/263 (26%)
		penumbra_like_LEL	114..234	CDD:239411	26/130 (20%)