Protein Alignment Tsp66E and tspan18b

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001002439.2
• Gene: tspan18b / 436712
• ZFINID: ZDB-GENE-040718-137
• Length: 258
• Species: Danio rerio
• Alignment Length: 269
• Identity: 77/269 - (28%)
• Similarity: 132/269 - (49%)
• Gaps: 48/269 - (17%)

  Fly     4 DCGVWCAKYLLCIFNFIFFVLGTIIFGVGLWLAVDK---HSLIALLKLVESERIEQFTQPQAIEQ 65
            || :.|.|||:.:|||:.|:.|:.:.|||:|:.||.   ..::|...|:       ||.
Zfish    16 DC-LSCIKYLMFVFNFLIFLGGSFLLGVGVWVVVDPTGFREIVAANPLL-------FTG------ 66

  Fly    66 LAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKN 130
             .|::|.:|.::|.:.|||..||:||::|||..:...::::.:||:.|..|...|::.:..|  .
Zfish    67 -VYIILAMGGMLFLLGFLGCCGAIRENKCLLLFFFMLILIIFLAELAAAILAFIFREHLTRE--Y 128

  Fly   131 FLQTTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDAS------PAWVNGKGNRTIPDAC 189
            |.:.....|....|.|..:..||.:|..|.|||:|...||:.|      |       :..:|:||
Zfish   129 FTKELKKHYQGYNNTDVFTSTWNAIMNTFDCCGVNSPEDFEESIFRIINP-------SEMVPEAC 186

  Fly   190 CILKD-VAKL-VPRDEDCTTNPSDSNSFYK--KGCYEVFTEWLIRQRELVIV---AIAVGIVHLV 247
            |...: |.:. ....|:|.:    .:..|:  ||||....::.    |:.|.   |:|:.::.:.
Zfish   187 CRRNNHVGESGFSNREECLS----GSMLYRNNKGCYSAVVDYF----EMYIYVAGALAIVVLTIE 243

  Fly   248 LIILAFALC 256
            |..:.||:|
Zfish   244 LFAMVFAMC 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	74/262 (28%)
		tetraspanin_LEL	120..228	CDD:351888	30/117 (26%)
tspan18b	NP_001002439.2	Tetraspanin	21..255	CDD:459767	74/263 (28%)
		uroplakin_I_like_LEL	118..229	CDD:239409	31/127 (24%)