Protein Alignment Tsp66E and tspan6

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_999939.1
• Gene: tspan6 / 406802
• ZFINID: ZDB-GENE-030131-5435
• Length: 251
• Species: Danio rerio
• Alignment Length: 257
• Identity: 68/257 - (26%)
• Similarity: 113/257 - (43%)
• Gaps: 39/257 - (15%)

  Fly     7 VWCAKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLL 71
            :.|.|..|..::.||:..|.|:..||:|..|:    :....||.||.         .....|||:
Zfish    14 ITCLKTFLISYSLIFWFTGVILLAVGVWGKVN----LEFDLLVNSEH---------GTNAPYVLI 65

  Fly    72 VIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTI 136
            ..|||:......|.....|.|..:|..|..||:|:.:||:|||..|..|:.:::|..|...|...
Zfish    66 GTGAVIIIFGLFGCFATCRGSPWMLKLYAMFLVLVFLAELVAGISGFIFRHEIKAVLKGAYQKAE 130

  Fly   137 TSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAKLVPR 201
            ::|...::.|.     :::.....|||..:|..: |:..:...:|   ||.:||       .|..
Zfish   131 SNYMGKDDEDL-----DRIQRTLQCCGEENYTSW-ANTTYFEKEG---IPKSCC-------NVTA 179

  Fly   202 DEDCTT------NPSDSNSFYKKGCYEVFTEWLIRQRELVIVA-IAVGIVHLVLIILAFALC 256
            ..:||:      ..:|| ..|.:||:.:.:..:  :..|.|:| |:.||....:|.:..|.|
Zfish   180 SVNCTSAELKDLKKADS-VVYHQGCFSLMSTTM--EANLGIIAGISFGIAFFQVIGIFLACC 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	67/253 (26%)
		tetraspanin_LEL	120..228	CDD:351888	24/113 (21%)
tspan6	NP_999939.1	Tetraspanin	17..241	CDD:459767	67/254 (26%)
		TM4SF2_6_like_LEL	112..215	CDD:239414	24/121 (20%)