Protein Alignment Tsp66E and cd81

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_989271.1
• Gene: cd81 / 394885
• XenbaseID: XB-GENE-946220
• Length: 237
• Species: Xenopus tropicalis
• Alignment Length: 265
• Identity: 74/265 - (27%)
• Similarity: 113/265 - (42%)
• Gaps: 48/265 - (18%)

  Fly     9 CAKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVI 73
            |.||||.:|||||::.|.:|.||.|||..|..:...|.:..|.:.     .|.......|:::.:
 Frog     9 CIKYLLFVFNFIFWLAGGVILGVALWLRHDPQTSNLLFQQFEDKH-----APGTFYIGVYIIIAV 68

  Fly    74 GAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQ----- 133
            ||||.|:.|||..||::||:|||.|:...|::|...|:.||..|...:|:|..|.:.|..
 Frog    69 GAVMMFVGFLGCYGAIQESQCLLGTFFACLVILFACEVAAGIWGFVNRDQVSKEMRLFYSEVYQH 133

  Fly   134 -TTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAK 197
             ||.|.....:.:.........|.    |||       |||   :......:|.|.|
 Frog   134 ATTGTKEQQQKALPVLKAFHETLQ----CCG-------DAS---LKKYVTMSITDMC-------- 176

  Fly   198 LVPRDEDCTTNPSDSNSFYK---KGCYEVFTEWLIRQRELV-IVAIAVGIVHLVLIILAFALCKA 258
                       |..||...:   :.|::........:..|| |.|:.|.::.::.:|.:..||..
 Frog   177 -----------PKRSNILEQITIEDCHQKIDVLFSTKLYLVGIAAVVVAVIMIIEMIFSMVLCCG 230

  Fly   259 FAKYN 263
            ...|:
 Frog   231 IRIYS 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	71/255 (28%)
		tetraspanin_LEL	120..228	CDD:351888	21/116 (18%)
cd81	NP_989271.1	Tetraspanin	10..229	CDD:459767	71/256 (28%)