Protein Alignment Tsp66E and TM4SF

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001261159.1
• Gene: TM4SF / 37786
• FlyBaseID: FBgn0020372
• Length: 292
• Species: Drosophila melanogaster
• Alignment Length: 269
• Identity: 58/269 - (21%)
• Similarity: 110/269 - (40%)
• Gaps: 78/269 - (28%)

  Fly     9 CAKYLLCIFNFIFFV---------LGT-IIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAI 63
            |.|||  :::::..:         ||| :::|..::..:.::.|.|               |.||
  Fly     9 CFKYL--VYSYVVLLALTGAAQIFLGTSLLWGHSVYYGIVQNKLWA---------------PAAI 56

  Fly    64 EQLAYVLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAES 128
                  ||.:|.|.|.:.::|.....:..||||..:...|:..:..:.:..|.....::.:....
  Fly    57 ------LLCLGPVTFILCWMGCQATNQRKRCLLGMFAALLVACICVQFIICGWSLAMRENLPTSV 115

  Fly   129 KNFLQTTITSYSLGENVDATSL----MWNQLMGNFGCCGIN---DYHDFDASPAWVNGKGNRTIP 186
            :.|:..:...:.  :....|.:    :||::.....|||::   ||.             ..::|
  Fly   116 EIFIDDSFVEFL--DKFSRTKVDNLHLWNRMQSQLQCCGVDGPLDYR-------------RLSLP 165

  Fly   187 DACCILKDVAKLVPRDEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELV------IVAI--AVGI 243
            .:||         .|.|....:..|::  ||:||..|.:| .||.|.|:      |:||  ::||
  Fly   166 WSCC---------SRPEHAYESACDTH--YKRGCLAVVSE-QIRNRLLITAFGAAIIAIFQSLGI 218

  Fly   244 ---VHLVLI 249
               |||.::
  Fly   219 FCAVHLTIL 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	57/267 (21%)
		tetraspanin_LEL	120..228	CDD:351888	21/114 (18%)
TM4SF	NP_001261159.1	Tetraspanin	10..224	CDD:459767	55/263 (21%)