Protein Alignment Tsp66E and tsp-21

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001370185.1
• Gene: tsp-21 / 259720
• WormBaseID: WBGene00023491
• Length: 301
• Species: Caenorhabditis elegans
• Alignment Length: 268
• Identity: 71/268 - (26%)
• Similarity: 120/268 - (44%)
• Gaps: 42/268 - (15%)

  Fly     7 VWCAKYLLCIF---NFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAY 68
            :|..|..:..|   |..|.:.|.....||:||...|::.|.|             .|.:...|:.
 Worm     7 IWNDKRKITYFFLANVCFLISGLSSLIVGVWLYSSKNNFIEL-------------TPTSYSALSA 58

  Fly    69 VLLVI--GAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDK----VRAE 127
            ..|.:  |..:|.:..:||||....::.||.:|..|:|||::...:|...|:..|::    :|..
 Worm    59 AGLCVFTGVTIFIIVAVGYLGVSWSNKSLLYSYIGFVILLILVHGIARITGSLHKEEAKENLRKS 123

  Fly   128 SKNFLQTTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCIL 192
            ..:.:.||.....:|..: ..||.|:.|.....|||:::|.|:..|..|.|   |...||:||
 Worm   124 MLHNINTTAVVTKIGREI-KLSLTWDHLQRELQCCGVDNYTDWHYSVHWPN---NLYTPDSCC-- 182

  Fly   193 KDVAKLVPR-------DEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELV-IVAIAVGIVHLVLI 249
                  .|:       .|:|...|.:.:..|:|||:..|::||.....|| .|...:.:|.::|:
 Worm   183 ------DPQHFDAENGTENCGKLPDEQSLLYQKGCFPKFSDWLYHHIILVNWVTSILFVVEILLL 241

  Fly   250 ILAFALCK 257
            ||:..:.:
 Worm   242 ILSLVVLR 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	70/262 (27%)
		tetraspanin_LEL	120..228	CDD:351888	31/118 (26%)
tsp-21	NP_001370185.1	Tetraspanin	17..>158	CDD:459767	39/154 (25%)
		CD151_like_LEL	106..223	CDD:239408	34/128 (27%)