Protein Alignment Tsp66E and Cd53

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_036655.1
• Gene: Cd53 / 24251
• RGDID: 2310
• Length: 219
• Species: Rattus norvegicus
• Alignment Length: 245
• Identity: 60/245 - (24%)
• Similarity: 110/245 - (44%)
• Gaps: 50/245 - (20%)

  Fly    11 KYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVIGA 75
            ||:|..|||:|:|.|..|.|.|:.|.|.....|....|             ....|..||:::|:
  Rat    10 KYVLFFFNFLFWVCGCCILGFGIHLLVQNTYGILFRNL-------------PFLTLGNVLVIVGS 61

  Fly    76 VMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSYS 140
            ::..::|||.:|:::|::|||.::...|:|:|:||:....|...::.|:.......|..:|..|
  Rat    62 IIMVVAFLGCMGSIKENKCLLMSFFVLLLLILLAEVTLAILLFVYEKKINTLVAEGLNDSIQHY- 125

  Fly   141 LGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAKLVPRDEDC 205
              .:.::|.:.|:.:.....|||:|...|      |::|.     |.:|
  Rat   126 --HSDNSTRMAWDFIQSQLQCCGVNGSSD------WISGP-----PSSC---------------- 161

  Fly   206 TTNPSDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGIVHLVLIILAFAL 255
               ||.::   .:|||:....| .....|.|..:.:.:..:.::.::|||
  Rat   162 ---PSGAD---VQGCYKKGQAW-FHSNFLYIGIVTICVCVIQVLGMSFAL 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	60/245 (24%)
		tetraspanin_LEL	120..228	CDD:351888	20/107 (19%)
Cd53	NP_036655.1	Tetraspanin	9..208	CDD:459767	60/245 (24%)
		CD53_like_LEL	104..186	CDD:239417	22/118 (19%)