Protein Alignment Tsp66E and Tspan10

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_663338.2
• Gene: Tspan10 / 208634
• MGIID: 2384781
• Length: 332
• Species: Mus musculus
• Alignment Length: 275
• Identity: 73/275 - (26%)
• Similarity: 112/275 - (40%)
• Gaps: 52/275 - (18%)

  Fly     9 CAKYLLCIFNFIFFVLGTIIFGVGLW-LAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLV 72
            |.|||:.:.||:|.:...:....||| |.|.:...|.....|.       |.|.       ::||
Mouse    74 CVKYLIFLSNFLFSLPSLLALAAGLWGLTVKRSQGIGWGGPVP-------TDPM-------LMLV 124

  Fly    73 IGA-VMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTI 136
            :|. |:..:|..|.|||..|:.|||..|...::..|..|.:||.|.......::...|..|...|
Mouse   125 LGGLVVSVVSLSGCLGAFCENSCLLHWYCGAVLFCLALEALAGVLMVTLWKPLQDSLKYTLHAAI 189

  Fly   137 TSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFD-------ASPAWVNGKGNRTIPDACCILKD 194
            ..|  .::.|...|: :|:.....|||...|.|:.       :||    |....::|.:|||
Mouse   190 IHY--WDDPDLHFLL-DQVQLGLQCCGAVSYQDWQQNLYFNCSSP----GVQACSLPASCCI--- 244

  Fly   195 VAKLVPRDEDCTTNPS--------DSN----SFYKKGCYEVFTEWLIRQRELVI--VAIAVGIVH 245
                .|:::....|..        |.|    ..:.:||:....||| |.....|  .|:||.::.
Mouse   245 ----NPQEDGAVVNTQCGFGALGLDQNVAGQVVFLQGCWPALQEWL-RGNTGAIGDCAVAVVMIQ 304

  Fly   246 LVLIILAFALCKAFA 260
            ...::||..|.:|.|
Mouse   305 GTELLLAACLLRALA 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	70/268 (26%)
		tetraspanin_LEL	120..228	CDD:351888	26/126 (21%)
Tspan10	NP_663338.2	Tetraspanin	75..225	CDD:459767	46/166 (28%)
		oculospanin_like_LEL	171..290	CDD:239420	29/133 (22%)