Protein Alignment Tsp66E and tsp-7

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_492636.1
• Gene: tsp-7 / 192062
• WormBaseID: WBGene00006633
• Length: 232
• Species: Caenorhabditis elegans
• Alignment Length: 260
• Identity: 75/260 - (28%)
• Similarity: 118/260 - (45%)
• Gaps: 43/260 - (16%)

  Fly     6 GVWCAKYLLCIFNFIFFV--LGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAY 68
            ||...||||.:.|.:.:|  |..||.|..|.|..|.     :|.::..||:          ....
 Worm     5 GVTIVKYLLFLANLVLWVGGLSLIIVGSILQLKFDN-----VLDILGDERL----------ATPI 54

  Fly    69 VLLVIGAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQ 133
            :|||||::...:.|||..||:||:.||..::...|.||:..||.|..:|....|..|....|.||
 Worm    55 LLLVIGSLCTLLGFLGCCGAIRENYCLTVSFAVLLALLITCEIAAVIIGYALHDSFRLGIGNQLQ 119

  Fly   134 TTITSYSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAKL 198
            |.:..|.....|::.   |::....|.|||:.:..|      |:.   ..||||:||| :::
 Worm   120 TGMVRYHESRGVESA---WDKTHQLFECCGVTNSSD------WLT---FTTIPDSCCI-EEI--- 168

  Fly   199 VPRDEDCTTNPSDSNSFYKKGCYEVFTEWLIRQRELV--IVAIAVGIVHLVLIILAFALCKAFAK 261
                |.|.   .::...::.||.....:|:::...:|  |.|: :..:.||.:..|..|.|:..|
 Worm   169 ----EGCA---RENAPLFEPGCIHSVEQWVLKNGAMVGGICAV-LAAIQLVGVCFACCLSKSILK 225

  Fly   262  261
             Worm   226  225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	71/249 (29%)
		tetraspanin_LEL	120..228	CDD:351888	26/107 (24%)
tsp-7	NP_492636.1	Tetraspanin	9..221	CDD:459767	71/250 (28%)
		NET-5_like_LEL	104..195	CDD:239418	27/113 (24%)