Protein Alignment Tsp66E and Cd82

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_031682.1
• Gene: Cd82 / 12521
• MGIID: 104651
• Length: 266
• Species: Mus musculus
• Alignment Length: 290
• Identity: 57/290 - (19%)
• Similarity: 99/290 - (34%)
• Gaps: 114/290 - (39%)

  Fly    32 INATVRDPKDR----KKTDHLLAL-DGAKERLKL--------FKADLLDEGSFELAIDGCETVFH 83
            :..||::||.|    .:|....:| |.|:::|:.        .||.|  :...:..::..:|...
Mouse   504 VQPTVQEPKQRTPSPDRTSKRGSLPDAAQQQLEFLEGRKKQYMKAAL--QAKQKKDLEQAKTFLR 566

  Fly    84 TASPVAITVKTDPQVELINPAVNG-TINVLRTCTKVSSVKRVILTSSMAAVLAPETKLGPNDVVD 147
            ||..:      :|.:|   .|.:| |::|    :||.|                    .|.| .|
Mouse   567 TAKGL------EPMIE---AARSGKTVDV----SKVPS--------------------PPGD-ED 597

  Fly   148 ETFF----TNPSFAEERKQWY--------------------------VLSKTLAEDAAWRFAKDN 182
            |.|.    ::...:|:.::.|                          |...|..|:.|.:..|..
Mouse   598 EDFILVHHSDVQLSEKAEEVYTQLNKLLNEQHEKCVTYSKQFTHLGNVAETTKFENMAEKCKKSL 662

  Fly   183 EIDLIVLNPGLVTGPILQPTLNFSVAVIVELMKGKNPFNTTHHRFVDV------RDVALAHVKAL 241
            ||..:..|.|      |||.              |:.|....:|.|.:      .|:.:..||.:
Mouse   663 EILKLAQNRG------LQPP--------------KHHFEERTYRTVRIFPELSSTDMVVVIVKGM 707

  Fly   242 ETPSANGRYIIDGPVVTIKDIENVLREFFP 271
            ..|:.:|        |...|::..::..||
Mouse   708 NLPAPSG--------VATNDLDAYVKFDFP 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	53/274 (19%)
		tetraspanin_LEL	120..228	CDD:351888	23/137 (17%)
Cd82	NP_031682.1	Tetraspanin	24..253	CDD:459767
		CD37_CD82_like_LEL	106..228	CDD:239413