Protein Alignment Tsp66E and Upk1a

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_081091.1
• Gene: Upk1a / 109637
• MGIID: 98911
• Length: 257
• Species: Mus musculus
• Alignment Length: 224
• Identity: 48/224 - (21%)
• Similarity: 91/224 - (40%)
• Gaps: 36/224 - (16%)

  Fly    13 LLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVIGAVM 77
            ||.:.|.|..:.|..:|...:|:..|::.:..|:.:  |.:.:.|..       |::.:..|...
Mouse    18 LLVVGNIIILLSGLALFAETVWVTADQYRVYPLMGV--SGKDDVFAG-------AWIAIFCGFSF 73

  Fly    78 FFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITSYSL- 141
            |.::..|...|:...|.::.||...::::.|.|..:.......:|.:.:......:..:|.||.
Mouse    74 FVVASFGVGAALCRRRYMILTYLLLMLIVYIFECASCITSYTHRDYMVSNPSLITKQMLTYYSAD 138

  Fly   142 ---GENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVN-GKGNRTI--------PDACCILKD 194
               |:.:   :.:|:::|....|||.:...|      ||| ....|..        |..||  :.
Mouse   139 TDQGQEL---TRLWDRIMIEQECCGTSGPMD------WVNYTSAFRAATPEVVFPWPPLCC--RR 192

  Fly   195 VAKLVPRDED-CTTNPSDSNSFYKKGCYE 222
            ....:|.:|| |.....|  ..:.|||:|
Mouse   193 TGNFIPINEDGCRVGHMD--YLFTKGCFE 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	48/224 (21%)
		tetraspanin_LEL	120..228	CDD:351888	27/117 (23%)
Upk1a	NP_081091.1	Tetraspanin	23..>161	CDD:459767	28/149 (19%)
		uroplakin_I_like_LEL	111..229	CDD:239409	27/122 (22%)