Protein Alignment Tsp66E and TSPAN9

DIOPT Version :10

• Sequence 1: NP_523985.1
• Gene: Tsp66E / 39017
• FlyBaseID: FBgn0035936
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_047284080.1
• Gene: TSPAN9 / 10867
• HGNCID: 21640
• Length: 330
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 70/246 - (28%)
• Similarity: 115/246 - (46%)
• Gaps: 32/246 - (13%)

  Fly     9 CAKYLLCIFNFIFFVLGTIIFGVGLWLAVDKHSLIALLKLVESERIEQFTQPQAIEQLAYVLLVI 73
            |.||::.:||.||::.|..:.|||:||:|.:.:...            |:........|.:::.|
Human    99 CLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFAT------------FSPSFPSLSAANLVIAI 151

  Fly    74 GAVMFFMSFLGYLGAMRESRCLLSTYGTFLILLLIAEIVAGGLGAFFKDKVRAESKNFLQTTITS 138
            |.::....|||.|||::|::|||.::...|:::|:||::...|...:.|||...:|..|:..:..
Human   152 GTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLL 216

  Fly   139 YSLGENVDATSLMWNQLMGNFGCCGINDYHDFDASPAWVNGKGNRTIPDACCILKDVAKLVPRDE 203
            |....||...: .||.:.....|||:.||.|      |....|..|:||.||        :...:
Human   217 YHTENNVGLKN-AWNIIQAEMRCCGVTDYTD------WYPVLGENTVPDRCC--------MENSQ 266

  Fly   204 DCTTNPSDSNSFYKKGCYEVFTEWLIRQRELVIVAIAVGIVHLVLIILAFA 254
            .|..|.  :...::.||||....|....:.   |...||:..|::.||..|
Human   267 GCGRNA--TTPLWRTGCYEKVKMWFDDNKH---VLGTVGMCILIMQILGMA 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp66E	NP_523985.1	Tetraspanin	11..257	CDD:459767	69/244 (28%)
		tetraspanin_LEL	120..228	CDD:351888	29/107 (27%)
TSPAN9	XP_047284080.1	Tetraspanin	100..319	CDD:459767	69/245 (28%)
		NET-5_like_LEL	196..293	CDD:239418	30/113 (27%)