DRSC/TRiP Functional Genomics Resources

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Protein Alignment TrpA1 and YAR1

DIOPT Version :9

Sequence 1:NP_001261600.1 Gene:TrpA1 / 39015 FlyBaseID:FBgn0035934 Length:1232 Species:Drosophila melanogaster
Sequence 2:NP_015085.1 Gene:YAR1 / 855837 SGDID:S000006160 Length:200 Species:Saccharomyces cerevisiae


Alignment Length:245 Identity:57/245 - (23%)
Similarity:90/245 - (36%) Gaps:71/245 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   395 GADINALDKEHRSPLLLAASRSGWKTVHLLIRLGACISVKDAAARNVLHFVIMNGGRLTDFAEQV 459
            |.....||:|.:..::|.|            |.|...|:||.....|             ..|.:
Yeast     2 GLHSEPLDQEDQDTIILDA------------RAGDLDSLKDIFTTLV-------------SPELL 41

  Fly   460 ANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRS----LENLIR------LGACINLKNNNNES 514
            :.|:.        :|.||   :.||.|:.:|||.:    ||.:.|      |.|.:|..|....:
Yeast    42 STCKE--------SESDS---TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNT 95

  Fly   515 PLHFAARYGRYNTVRQLLDS-EKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGALLHRDH 578
            .||:|:..|:.:.|:.|.|. |...||.|:   .|...:..:...|...|....|.:..:...|.
Yeast    96 ALHWASLNGKLDVVKLLCDEYEADPFIRNK---FGHDAIFEAENSGKEEVETYFLKKYDVEPEDD 157

  Fly   579 ------TGRNPLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALHLAT 622
                  .|:|.:|:      |:..|         ::||.|:...||...|
Yeast   158 EEDTQTEGKNSVQI------TKGTE---------IEQVTKEATEALREET 192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TrpA1NP_001261600.1 Ank_2 95..188 CDD:289560
ANK 121..246 CDD:238125
ANK repeat 125..155 CDD:293786
ANK repeat 157..199 CDD:293786
Ank_2 230..330 CDD:289560
ANK repeat 259..298 CDD:293786
ANK 298..425 CDD:238125 6/29 (21%)
ANK repeat 300..330 CDD:293786
Ank_2 305..402 CDD:289560 1/6 (17%)
ANK repeat 336..369 CDD:293786
ANK repeat 374..402 CDD:293786 1/6 (17%)
ANK repeat 404..476 CDD:293786 12/71 (17%)
ANK 473..599 CDD:238125 37/142 (26%)
ANK repeat 478..509 CDD:293786 12/40 (30%)
Ank_2 483..572 CDD:289560 28/99 (28%)
ANK repeat 511..545 CDD:293786 11/34 (32%)
ANK 542..662 CDD:238125 17/87 (20%)
ANK repeat 547..576 CDD:293786 4/28 (14%)
Ank_2 552..643 CDD:289560 15/77 (19%)
ANK repeat 579..611 CDD:293786 6/31 (19%)
ANK repeat 613..638 CDD:293786 3/10 (30%)
Ion_trans 858..1074 CDD:278921
YAR1NP_015085.1 ANK repeat 11..47 CDD:293786 11/68 (16%)
Ank_2 20..124 CDD:403870 35/139 (25%)
ANK repeat 49..90 CDD:293786 14/43 (33%)
ANK repeat 92..124 CDD:293786 10/31 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2336
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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