DRSC/TRiP Functional Genomics Resources

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Protein Alignment TrpA1 and trpa-2

DIOPT Version :9

Sequence 1:NP_001261600.1 Gene:TrpA1 / 39015 FlyBaseID:FBgn0035934 Length:1232 Species:Drosophila melanogaster
Sequence 2:NP_492031.1 Gene:trpa-2 / 3565192 WormBaseID:WBGene00010873 Length:481 Species:Caenorhabditis elegans


Alignment Length:448 Identity:91/448 - (20%)
Similarity:168/448 - (37%) Gaps:140/448 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   708 KANCKKDSKSFYIKYSFAFLQCPFMFAKIDEKTGESITTASPIPLPALNTMVTHGRVELLAHPLS 772
            :.|..:||.:|...|              :..:||::....      |..:.:..:..::.||..
 Worm    34 RRNKAEDSTTFIFNY--------------ENGSGETLNWKE------LRKLKSGKKWGVIRHPYI 78

  Fly   773 QKYLQMKWNSYGKYF--HLANLLIYSIFLVF------------VTIYSSLMMNNIELKAGDNKTM 823
            ..|:..|......::  |:...|::.:.|.:            :||::.:....:.||.      
 Worm    79 LNYVNQKLIDCAFFYSLHILAFLVFFLLLAWHVFSRNLFKDFLITIFTGIFFMFLVLKG------ 137

  Fly   824 SQYCNMGWEQLTMNLSQNPSVASQIRLDSCEERINRTTAILFCAVVIVVYILLNSMRELIQIYQQ 888
                                        :.:.||.::.:..|  :|...:.:...|..|..::..
 Worm   138 ----------------------------TIKARITKSVSTWF--IVAFCFNIFTYMATLAYVWLP 172

  Fly   889 KL----HYILETVNLISWVLYISALVMVTPAFQPDGGINTIHYSAASIAVFLSWFRLLLFLQRFD 949
            .:    .|.||...:::|.|.|                         ||:..:|.. ||::.|..
 Worm   173 TVFGYDDYHLEVKKIVTWFLPI-------------------------IAIISAWAN-LLYIMRKS 211

  Fly   950 QVGIYVVMFLEILQTLIKVLMVFSILIIAFGLAFYILLS-------KIIDPQPNHLSFSNIPMSL 1007
            ..|||:.|...||::...:..::...:|||..||.:::.       .:||.|..:::.....:.:
 Worm   212 PFGIYIFMMTRILRSFAHIATIWIPTLIAFSFAFLLIMRDTGVKPWPLIDQQTENMTMVQTMLVI 276

  Fly  1008 L----RTFSMMLGELDFVGTYVNTYYRDQLKVPMTSFLILSVFMILMPILLMNLLIGLAVGDIES 1068
            |    :|.:||:||:|     .|........:|  |.|:| ||.|:..||||||::.|||||:..
 Worm   277 LQAVTKTSTMMIGEVD-----ANDILDTNQWIP--SILVL-VFEIITVILLMNLMVSLAVGDVTY 333

  Fly  1069 VRRNAQLKRL---------AMQVV---------LHTELERKLPHVWLQRVDKMELIEY 1108
            :...||.|.|         |:|:.         |||   :|.|:|.:...|...:.|:
 Worm   334 LNNTAQDKLLKIKVNFVIEALQISEQFQNEMFRLHT---KKTPNVLVINSDGTYISEF 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TrpA1NP_001261600.1 Ank_2 95..188 CDD:289560
ANK 121..246 CDD:238125
ANK repeat 125..155 CDD:293786
ANK repeat 157..199 CDD:293786
Ank_2 230..330 CDD:289560
ANK repeat 259..298 CDD:293786
ANK 298..425 CDD:238125
ANK repeat 300..330 CDD:293786
Ank_2 305..402 CDD:289560
ANK repeat 336..369 CDD:293786
ANK repeat 374..402 CDD:293786
ANK repeat 404..476 CDD:293786
ANK 473..599 CDD:238125
ANK repeat 478..509 CDD:293786
Ank_2 483..572 CDD:289560
ANK repeat 511..545 CDD:293786
ANK 542..662 CDD:238125
ANK repeat 547..576 CDD:293786
Ank_2 552..643 CDD:289560
ANK repeat 579..611 CDD:293786
ANK repeat 613..638 CDD:293786
Ion_trans 858..1074 CDD:278921 56/230 (24%)
trpa-2NP_492031.1 Ion_trans 119..339 CDD:278921 62/289 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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