DRSC/TRiP Functional Genomics Resources

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Protein Alignment TrpA1 and Dysf

DIOPT Version :9

Sequence 1:NP_001261600.1 Gene:TrpA1 / 39015 FlyBaseID:FBgn0035934 Length:1232 Species:Drosophila melanogaster
Sequence 2:XP_017448118.1 Gene:Dysf / 312492 RGDID:1311023 Length:2148 Species:Rattus norvegicus


Alignment Length:441 Identity:85/441 - (19%)
Similarity:141/441 - (31%) Gaps:154/441 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 LEAILPAE----PPAEV----------------CLLRD------SPFRILRAAESGNLDDFKRLF 111
            :|.:||.|    ||..|                |.:|.      .|:.....:..|..||...|.
  Rat  1434 MEVMLPREDLYCPPIVVKVIDNRQFGRRPVVGQCTIRSLENFLCDPYSAESPSPQGGPDDVSLLS 1498

  Fly   112 MADNSRIALKDAKGRTAAHQA---AARNRVNIL---------RYI------------RDQNGDFN 152
            ..::..|.:.|.:.......|   ::....|::         .:|            |::.|.:.
  Rat  1499 PGEDVLIDIDDKEPLIPVQLADGLSSLGPTNLMPSPSSPHEEEFIDWWSKFFASIGEREKCGSYL 1563

  Fly   153 AKD----NAGNTPLHIAVESDAYDAL-DYLLSIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQ 212
            .||    ...:|.|.   ..:|:..| |:..:..:..|...|..:.|             .|:|:
  Rat  1564 EKDFDTLKVYDTQLE---NVEAFGGLSDFCNTFKLYRGKTQEDTEDP-------------SVIGE 1612

  Fly   213 YRNVIDIQQGGEHGRTAL-----HLAAIYDHEEC-ARI-LITEFDACPRKPCNNG----YYPIHE 266
            ::.:..|....|.....:     |..|....:|| .|| :|..|...|:.|  ||    |..|..
  Rat  1613 FKGLFKIYPLPEDPAIPMPPRQFHQLAAQGPQECLVRIYIIRAFGLQPKDP--NGKCDPYIKISI 1675

  Fly   267 AAKNASSK------TMEVFFQWGEQRGCT----REEMISFYD----------SEGNVPLHSAVHG 311
            ..|:.|.:      |:|..|....:..||    ::..|:.||          .|..:.|.:    
  Rat  1676 GKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVIDLEN---- 1736

  Fly   312 GDIKAVELCLKSGAKIS-TQQHDLSTP------------VHLACAQGAIDIV-----KLMFE--- 355
                  .|..|.||:.. .|.:.:|.|            :||.|.|..:...     ::.|:   
  Rat  1737 ------RLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVYRTDRVTFQDKE 1795

  Fly   356 ---------------MQPMEKRLCLSCTDVQKMTPLHCAS--MFD--HPDI 387
                           :.|:|:||.|.....|.:.|.|..|  ::.  .|||
  Rat  1796 YTIQEIEAGRLPNPHLGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDI 1846

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TrpA1NP_001261600.1 Ank_2 95..188 CDD:289560 19/121 (16%)
ANK 121..246 CDD:238125 26/160 (16%)
ANK repeat 125..155 CDD:293786 5/53 (9%)
ANK repeat 157..199 CDD:293786 8/42 (19%)
Ank_2 230..330 CDD:289560 30/131 (23%)
ANK repeat 259..298 CDD:293786 12/52 (23%)
ANK 298..425 CDD:238125 27/140 (19%)
ANK repeat 300..330 CDD:293786 6/30 (20%)
Ank_2 305..402 CDD:289560 25/123 (20%)
ANK repeat 336..369 CDD:293786 11/67 (16%)
ANK repeat 374..402 CDD:293786 6/18 (33%)
ANK repeat 404..476 CDD:293786
ANK 473..599 CDD:238125
ANK repeat 478..509 CDD:293786
Ank_2 483..572 CDD:289560
ANK repeat 511..545 CDD:293786
ANK 542..662 CDD:238125
ANK repeat 547..576 CDD:293786
Ank_2 552..643 CDD:289560
ANK repeat 579..611 CDD:293786
ANK repeat 613..638 CDD:293786
Ion_trans 858..1074 CDD:278921
DysfXP_017448118.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1326
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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