DRSC/TRiP Functional Genomics Resources

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Protein Alignment TrpA1 and Sowahc

DIOPT Version :9

Sequence 1:NP_001261600.1 Gene:TrpA1 / 39015 FlyBaseID:FBgn0035934 Length:1232 Species:Drosophila melanogaster
Sequence 2:NP_766527.3 Gene:Sowahc / 268301 MGIID:3606051 Length:512 Species:Mus musculus


Alignment Length:195 Identity:53/195 - (27%)
Similarity:88/195 - (45%) Gaps:31/195 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   474 EKDSMGCS----PLHYA----SRDGHIRSLENLIRLGACINLKNN--NNESPLHFAARYGRYNTV 528
            |:.|:|.|    ||.:|    :.:|...|||.|:.....:..|.:  ...:.||:||::||...:
Mouse   241 EESSVGASVTLDPLDHAWMLSASEGKWDSLEGLLTCEPGLLSKRDFITGFTCLHWAAKHGRQELL 305

  Fly   529 RQLLD---SEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGA----LLHRDHTGRNPLQL 586
            ..|::   ..:....||.....|.|.||:::..||..||:||:  ||    :..||::||...|.
Mouse   306 AMLVNFATKHQLPVNINAKSSGGYTALHLAAMHGHVEVVKLLV--GAYDADVDIRDYSGRKASQY 368

  Fly   587 AAMSGYTETIELLHSVHSHLLDQVDKD-------GNTALHLATMENKPHAISVLMSMGCKLVYNV 644
            .:.|...|...|:.:     ||:.|.|       |...|......:..|.:|.::..|.:|.::|
Mouse   369 LSESIAEEIKNLVGA-----LDEDDGDSPAARGGGRWRLSKVLPSHITHKLSPVVEDGAELHHHV 428

  Fly   645  644
            Mouse   429  428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TrpA1NP_001261600.1 Ank_2 95..188 CDD:289560
ANK 121..246 CDD:238125
ANK repeat 125..155 CDD:293786
ANK repeat 157..199 CDD:293786
Ank_2 230..330 CDD:289560
ANK repeat 259..298 CDD:293786
ANK 298..425 CDD:238125
ANK repeat 300..330 CDD:293786
Ank_2 305..402 CDD:289560
ANK repeat 336..369 CDD:293786
ANK repeat 374..402 CDD:293786
ANK repeat 404..476 CDD:293786 1/1 (100%)
ANK 473..599 CDD:238125 41/141 (29%)
ANK repeat 478..509 CDD:293786 10/38 (26%)
Ank_2 483..572 CDD:289560 27/97 (28%)
ANK repeat 511..545 CDD:293786 9/36 (25%)
ANK 542..662 CDD:238125 32/114 (28%)
ANK repeat 547..576 CDD:293786 12/32 (38%)
Ank_2 552..643 CDD:289560 28/101 (28%)
ANK repeat 579..611 CDD:293786 8/31 (26%)
ANK repeat 613..638 CDD:293786 5/31 (16%)
Ion_trans 858..1074 CDD:278921
SowahcNP_766527.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 126..248 3/6 (50%)
Ank_2 259..359 CDD:289560 27/101 (27%)
ANK 288..397 CDD:238125 33/115 (29%)
ANK 1 288..317 7/28 (25%)
ANK repeat 289..325 CDD:293786 9/35 (26%)
ANK repeat 327..359 CDD:293786 12/33 (36%)
ANK 2 327..357 12/31 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 427..500 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2336
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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