Protein Alignment Mcm7 and MCM3

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_010882.1
• Gene: MCM3 / 856680
• SGDID: S000000758
• Length: 971
• Species: Saccharomyces cerevisiae
• Alignment Length: 784
• Identity: 251/784 - (32%)
• Similarity: 372/784 - (47%)
• Gaps: 169/784 - (21%)

  Fly     4 RDYAQDRESIKTFLSEFCKCDDDG-----KKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLA 63
            :|.|.:|:.:.         ||||     :|:....:.|..|.||    |.|.||||.||:.
Yeast    60 QDDADERDLLG---------DDDGDDLEKEKKAASSTSLNILPHR----IIISLDDLREFDR--- 108

  Fly    64 EAVVDNCRRYTSIFSDVIAE---LLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNS 125
                       |.:|.::.|   .:|..::......|::| .:.|.......:|:|
Yeast   109 -----------SFWSGILVEPAYFIPPAEKALTDLADSMD-DVPHPNASAVSSRHP--------- 152

  Fly   126 FPSELMKRFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGSE 190
                    :::.||......|.|.|.:.|||:.|||:|.||||:.:.|:|.::.:.:...:.|..
Yeast   153 --------WKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRF 209

  Fly   191 TYQPVNSLSFT--------PVHDCPSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVG 247
            .|:.....:.|        .::  |::|..    |.:|..:...|.|:..|.:.:||..:..|.|
Yeast   210 HYRDYTDATTTLTTRIPTPAIY--PTEDTE----GNKLTTEYGYSTFIDHQRITVQEMPEMAPAG 268

  Fly   248 HIPRSMTIMCRGEVTRMAQPGDHIVVSGVFLPLMRTGFAQMIQG--------LLSETFLQAH-RI 303
            .:|||:.::...::....:|||.:.|.|||..|...|..|....        :|..|....| |.
Yeast   269 QLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARS 333

  Fly   304 ICINKNDEISDKDAELTPEELEELA-QDDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDKR-P 366
            ..:.....::|.|.    ..:.:|: :.|.::.|:.||||.||||..:|||:||:|:|||:|. .
Yeast   334 TGVAARQMLTDFDI----RNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLE 394

  Fly   367 DGMKIRGNINICLMGDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEG 431
            :|..:||:|||.::|||..||||||.::...|..:..|||||||||||||||..|..|||..||.
Yeast   395 NGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEA 459

  Fly   432 GALVLADQGVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYN 496
            ||:||||:||.||||||||.|.||.||||||||||::||||||.||||||.|::|||||.||:|:
Yeast   460 GAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYD 524

  Fly   497 PRRTVEQNIQLPAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSHSKQPP------------- 548
            ..|...|||.||.:||||||||:::.|..:...|..:::|:  :.:|...||
Yeast   525 VNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHV--LRTHRYLPPGYLEGEPVRERLN 587

  Fly   549 ---------------------------------------------------------TRV-KALD 555
                                                                     |.: |.:.
Yeast   588 LSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVT 652

  Fly   556 MNLMRRYINLCK-RKNPTIPDELTDYIVGAYVELRREARNQKDMTFTSARNLLGILRLSTALARL 619
            :..:|:|:...| |..|.:..|..:.||..|.:||.:...:|..  .:||.|..::||:||.|::
Yeast   653 IPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSP--ITARTLETLIRLATAHAKV 715

  Fly   620 RLSDSVEKDD---VAEALRLLEMSKDSLNQIHEHQKGH-------VPNTSDRIFAIVRELA-GSG 673
            |||.:|.|.|   .|..||...:.:|..|.|.|.:..:       .|..|.:....||:.| .||
Yeast   716 RLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSG 780

  Fly   674 KAVK 677
            ..:|
Yeast   781 SPIK 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	21/91 (23%)
		MCM	145..641	CDD:214631	208/589 (35%)
MCM3	NP_010882.1	MCM_N	25..>137	CDD:405270	25/103 (24%)
		MCM	166..738	CDD:214631	207/585 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810