Protein Alignment Mcm7 and Mcm9

DIOPT Version :9

• Sequence 1: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_082106.3
• Gene: Mcm9 / 71567
• MGIID: 1918817
• Length: 1134
• Species: Mus musculus
• Alignment Length: 647
• Identity: 194/647 - (29%)
• Similarity: 318/647 - (49%)
• Gaps: 115/647 - (17%)

  Fly    80 VIAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNP---------------MEQRDERNSFPSE 129
            ::.::..|| ..|.|..|.|       |:::.|..:.               ||..|....||:|
Mouse     8 LVGQVFESY-VSEYHKNDIL-------LILKERDEDAHYPVVVNAMSLFETNMEIGDYFTVFPNE 64

  Fly   130 LMKRFEVGFKPLSTEKAHSIREV----------------------------KAQHIGKLVTVRGI 166
            ::..|:...:..:.....|:.|.                            |.:.:|..::|.|.
Mouse    65 VLTVFDSALRRSALAILQSLPETEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGT 129

  Fly   167 VTRCTEVKPMMVVATYTCDRC--------GSETYQPVNSLSFTPVHDCPS-DDCRVNKAGGRLYL 222
            |.|.:.||.:.....|.|::|        ..|.|     .:|:....||| ..|..:|......|
Mouse   130 VIRTSLVKVLEFERDYMCNKCKHVFMVEADFEQY-----YTFSRPSSCPSLASCDSSKFSCLSDL 189

  Fly   223 QTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVTRMAQPGDHIVVSGVFL----PLMRT 283
            .:..::...:||:|:||...::.||.|||||.::...::....:.||.:.:.||.:    |..|.
Mouse   190 SSSPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRD 254

  Fly   284 GFAQMIQGLLSETFLQAHRIICINKNDE--ISDKDAELTPEELEELAQDDFYE-----------R 335
            ...::      |..|:|:.:...|:...  :.|:|   |.:|.|     ||:|           .
Mouse   255 VRCEV------EIVLKANYVQVNNEQSSGMVMDED---TRKEFE-----DFWEHYKSDPFAGRNE 305

  Fly   336 LATSLAPEIYGHLDVKKALLLLLVGGVDKRPD--GMKIRGNINICLMGDPGVAKSQLLGYISRLA 398
            :..||.|:::|...||.|:.::|.||: :|.|  |.::||..::.|:||||..|||.|.|.:::.
Mouse   306 ILASLCPQVFGMYLVKLAVAMVLAGGI-QRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKIT 369

  Fly   399 VRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCIDEFDKMADQDRTAIHEVME 463
            .||..|||.||:..|||...:||  :||..||.|||||||.|:||||||:.:.:.|||:|||.||
Mouse   370 PRSVLTTGIGSTSAGLTVTAVKD--SGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAME 432

  Fly   464 QQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPAALLSRFDLLWLIQDKPDRD 528
            |||||:||||::..||.|.:||||.||. |:|:|:.:|..||.|.:.|||||||:.::.|..:.|
Mouse   433 QQTISVAKAGLVCKLNTRTTILAATNPK-GQYDPKESVSVNIALGSPLLSRFDLVLVLLDTRNED 496

  Fly   529 NDLRLAKHITYVHSHSKQPPTRVKAL-DMNLMRRYINLCKRKNPTIPDELTDYIVGAYVELRREA 592
            .|..::..|.    .:|..|::.:.| .|..|:.|..|.:..:||: .|:::.::..|.:::|::
Mouse   497 WDRIISSFIL----ENKGYPSKSENLWSMEKMKTYFCLIRNLHPTL-SEVSNQVLLRYYQMQRQS 556

  Fly   593 RNQKDMTFTSARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMSKD------SLNQIH 648
             :.::...|:.|.|..::||:.|.|||....:|..:|...|:.::|.|..      .:|.:|
Mouse   557 -DSRNAARTTIRLLESLIRLAEAHARLMFRSAVTLEDAVTAVSVMESSMQGGALLGGVNALH 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	4/16 (25%)
		MCM	145..641	CDD:214631	176/552 (32%)
Mcm9	NP_082106.3	Mcm2	10..605	CDD:224162	192/631 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	659..1101
		DUF4045	<739..>1004	CDD:330572

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010